Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolution
…, WW Hannon, AN Loes, K Hauser, JR Dillen, E Ferri… - Science, 2022 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved variants with
substitutions in the spike receptor-binding domain (RBD) that affect its affinity for angiotensin-…
substitutions in the spike receptor-binding domain (RBD) that affect its affinity for angiotensin-…
Predicting the mutational drivers of future SARS-CoV-2 variants of concern
SARS-CoV-2 evolution threatens vaccine- and natural infection–derived immunity and the
efficacy of therapeutic antibodies. To improve public health preparedness, we sought to …
efficacy of therapeutic antibodies. To improve public health preparedness, we sought to …
Bromodomains: Structure, function and pharmacology of inhibition
E Ferri, C Petosa, CE McKenna - Biochemical pharmacology, 2016 - Elsevier
Bromodomains are epigenetic readers of histone acetylation involved in chromatin
remodeling and transcriptional regulation. The human proteome comprises 46 bromodomain-…
remodeling and transcriptional regulation. The human proteome comprises 46 bromodomain-…
[HTML][HTML] A pan-influenza antibody inhibiting neuraminidase via receptor mimicry
Rapidly evolving influenza A viruses (IAVs) and influenza B viruses (IBVs) are major causes
of recurrent lower respiratory tract infections. Current influenza vaccines elicit antibodies …
of recurrent lower respiratory tract infections. Current influenza vaccines elicit antibodies …
[HTML][HTML] HOLMES: The electron capture decay of Ho to measure the electron neutrino mass with sub-eV sensitivity
…, M De Gerone, R Dressler, M Faverzani, E Ferri… - The European Physical …, 2015 - Springer
The European Research Council has recently funded HOLMES, a new experiment to
directly measure the neutrino mass. HOLMES will perform a calorimetric measurement of the …
directly measure the neutrino mass. HOLMES will perform a calorimetric measurement of the …
Identification of a novel BET bromodomain inhibitor‐sensitive, gene regulatory circuit that controls Rituximab response and tumour growth in aggressive lymphoid …
Immuno‐chemotherapy elicit high response rates in B‐cell non‐Hodgkin lymphoma but
heterogeneity in response duration is observed, with some patients achieving cure and others …
heterogeneity in response duration is observed, with some patients achieving cure and others …
[HTML][HTML] Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α
Inositol requiring enzyme 1 (IRE1) mitigates endoplasmic-reticulum (ER) stress by
orchestrating the unfolded-protein response (UPR). IRE1 spans the ER membrane, and signals …
orchestrating the unfolded-protein response (UPR). IRE1 spans the ER membrane, and signals …
Luminescent conjugates between dinuclear rhenium (I) complexes and peptide nucleic acids (PNA) for cell imaging and DNA targeting
E Ferri, D Donghi, M Panigati, G Prencipe… - Chemical …, 2010 - pubs.rsc.org
New luminescent dinuclear rhenium(I) tricarbonyl complex–PNA conjugates have been
synthesized through a reliable solid-phase synthetic methodology. Their photophysical …
synthesized through a reliable solid-phase synthetic methodology. Their photophysical …
Pulmonary Nodules: Volume Repeatability at Multidetector CT Lung Cancer Screening1
…, G Di Tolla, LF Frigerio, C Morosi, F Tafaro, E Ferri… - Radiology, 2009 - pubs.rsna.org
Purpose: To assess in vivo volumetric repeatability of an automated software algorithm in
pulmonary nodules detected during a lung cancer screening trial. Materials and Methods: This …
pulmonary nodules detected during a lung cancer screening trial. Materials and Methods: This …
The HOLMES experiment
…, PK Day, M De Gerone, R Dressler, E Ferri… - Journal of Low …, 2016 - Springer
The determination of the neutrino mass is an open issue in modern particle physics and
astrophysics. The direct mass measurement is the only theory-unrelated experimental tool …
astrophysics. The direct mass measurement is the only theory-unrelated experimental tool …