User profiles for Elena I. Frolova

Elena I Frolova

University of Alabama at Birmingham
Verified email at uab.edu
Cited by 5745

Roles of nonstructural protein nsP2 and alpha/beta interferons in determining the outcome of Sindbis virus infection

EI Frolova, RZ Fayzulin, SH Cook, DE Griffin… - Journal of …, 2002 - Am Soc Microbiol
Alphaviruses productively infect a variety of vertebrate and insect cell lines. In vertebrate
cells, Sindbis virus redirects cellular processes to meet the needs of virus propagation. At the …

Evasion of the innate immune response: the Old World alphavirus nsP2 protein induces rapid degradation of Rpb1, a catalytic subunit of RNA polymerase II

I Akhrymuk, SV Kulemzin, EI Frolova - Journal of virology, 2012 - Am Soc Microbiol
The Old World alphaviruses are emerging human pathogens with an ability to cause widespread
epidemics. The latest epidemic of Chikungunya virus, from 2005 to 2007, affected over …

Functional Sindbis virus replicative complexes are formed at the plasma membrane

EI Frolova, R Gorchakov, L Pereboeva… - Journal of …, 2010 - Am Soc Microbiol
Formation of virus-specific replicative complexes (RCs) in infected cells is one of the most
intriguing and important processes that determine virus replication and ultimately their …

Digitalization of education in modern scientific discourse: new trends and risks analysis.

EV Frolova, OV Rogach, TM Ryabova - European journal of contemporary …, 2020 - ERIC
The paper presents the results of systematic review of modern scientific publications devoted
to the digitalization of education. A review of Russian and foreign studies allows us to …

β-d-N4-Hydroxycytidine Is a Potent Anti-alphavirus Compound That Induces a High Level of Mutations in the Viral Genome

…, MR Crowley, GR Painter, EI Frolova… - Journal of …, 2018 - Am Soc Microbiol
Venezuelan equine encephalitis virus (VEEV) is a representative member of the New World
alphaviruses. It is transmitted by mosquito vectors and causes highly debilitating disease in …

[HTML][HTML] Purification and primary structure of two isoforms of arenicin, a novel antimicrobial peptide from marine polychaeta Arenicola marina

…, AD Krasnosdembskaya, ML Markelov, EI Frolova… - FEBS letters, 2004 - Elsevier
Two novel 21-residue antimicrobial peptides, arenicin-1 and arenicin-2, exhibiting activity
against Gram-positive and Gram-negative bacteria and fungi, were purified from coelomocytes …

Interferon-stimulated poly (ADP-Ribose) polymerases are potent inhibitors of cellular translation and virus replication

S Atasheva, EI Frolova, I Frolov - Journal of virology, 2014 - Am Soc Microbiol
The innate immune response is the first line of defense against most viral infections. Its
activation promotes cell signaling, which reduces virus replication in infected cells and leads to …

[HTML][HTML] New World and Old World alphaviruses have evolved to exploit different components of stress granules, FXR and G3BP proteins, for assembly of viral …

…, I Akhrymuk, JA Mobley, I Frolov, EI Frolova - PLoS …, 2016 - journals.plos.org
The positive-strand RNA viruses initiate their amplification in the cell from a single genome
delivered by virion. This single RNA molecule needs to become involved in replication …

New PARP gene with an anti-alphavirus function

S Atasheva, M Akhrymuk, EI Frolova, I Frolov - Journal of virology, 2012 - Am Soc Microbiol
Alphaviruses represent a highly important group of human and animal pathogens, which
are transmitted by mosquito vectors between vertebrate hosts. The hallmark of alphavirus …

Venezuelan equine encephalitis virus capsid protein forms a tetrameric complex with CRM1 and importin α/β that obstructs nuclear pore complex function

S Atasheva, A Fish, M Fornerod, EI Frolova - Journal of virology, 2010 - Am Soc Microbiol
ABSTRACT Development of the cellular antiviral response requires nuclear translocation of
multiple transcription factors and activation of a wide variety of cellular genes. To counteract …