Ovarian cancer (OvCa) develops asymptomatically until it reaches the advanced stages with
metastasis, chemoresistance, and poor prognosis. Our review focuses on the analysis of …

CCR8 is a chemokine receptor expressed principally on regulatory T cells (Treg) and is
known to be critical for CCR8 + Treg-mediated immunosuppression. Recent studies have …

Long noncoding RNAs (lncRNAs) have been identified as contributors to the development
and progression of cancer through various functions and mechanisms. LncRNA GAS5 is …

Evolutionary theory suggests that lifespan-reducing alleles should be purged from the gene
pool, and yet decades of genome-wide association and model organism studies have …

Methylation of promoter CpG islands may suppress the function of miRNAs by inhibiting their
expression. Our work analyzes the role of promoter methylation in altering the expression …

A decrease in the miR-124 expression was observed in various epithelial cancers. Like a
classical suppressor, miR-124 can inhibit the translation of multiple oncogenic proteins. …

The fundamental novelty in the pathogenesis of renal cell carcinoma (RCC) was discovered
as a result of the recent identification of the role of long non-coding RNAs (lncRNAs). Here, …

Our work aimed to differentiate 20 aberrantly methylated miRNA genes that participate at
different stages of development and metastasis of ovarian carcinoma (OvCa) using methylation-…

Elenagen is a plasmid encoding p62/SQSTM1, the first DNA vaccine possessing two
mutually complementing mechanisms of action: it elicits immune response against p62 and …

Ovarian cancer (OC) is one of the most common types of cancer among malignancies of the
female reproductive system. This pathology is asymptomatic until advanced stages and has …