[HTML][HTML] LncRNAs in ovarian cancer progression, metastasis, and main pathways: ceRNA and alternative mechanisms
…, MV Fridman, AA Moscovtsev, EA Filippova… - International journal of …, 2020 - mdpi.com
Ovarian cancer (OvCa) develops asymptomatically until it reaches the advanced stages with
metastasis, chemoresistance, and poor prognosis. Our review focuses on the analysis of …
metastasis, chemoresistance, and poor prognosis. Our review focuses on the analysis of …
Targeting CCR8 induces protective antitumor immunity and enhances vaccine-induced responses in colon cancer
…, A L'Huillier, S Armington, C Mottershead, EV Filippova… - Cancer research, 2018 - AACR
CCR8 is a chemokine receptor expressed principally on regulatory T cells (Treg) and is
known to be critical for CCR8 + Treg-mediated immunosuppression. Recent studies have …
known to be critical for CCR8 + Treg-mediated immunosuppression. Recent studies have …
[HTML][HTML] Long noncoding RNA GAS5 in breast cancer: Epigenetic mechanisms and biological functions
EA Filippova, MV Fridman, AM Burdennyy… - International journal of …, 2021 - mdpi.com
Long noncoding RNAs (lncRNAs) have been identified as contributors to the development
and progression of cancer through various functions and mechanisms. LncRNA GAS5 is …
and progression of cancer through various functions and mechanisms. LncRNA GAS5 is …
Dietary stress remodels the genetic architecture of lifespan variation in outbred Drosophila
Evolutionary theory suggests that lifespan-reducing alleles should be purged from the gene
pool, and yet decades of genome-wide association and model organism studies have …
pool, and yet decades of genome-wide association and model organism studies have …
Novel miRNA genes deregulated by aberrant methylation in ovarian carcinoma are involved in metastasis
VI Loginov, IV Pronina, AM Burdennyy, EA Filippova… - Gene, 2018 - Elsevier
Methylation of promoter CpG islands may suppress the function of miRNAs by inhibiting their
expression. Our work analyzes the role of promoter methylation in altering the expression …
expression. Our work analyzes the role of promoter methylation in altering the expression …
[HTML][HTML] Regulation of the key epithelial cancer suppressor miR-124 function by competing endogenous RNAs
…, MV Fridman, AM Burdennyy, EA Filippova… - International journal of …, 2022 - mdpi.com
A decrease in the miR-124 expression was observed in various epithelial cancers. Like a
classical suppressor, miR-124 can inhibit the translation of multiple oncogenic proteins. …
classical suppressor, miR-124 can inhibit the translation of multiple oncogenic proteins. …
[HTML][HTML] LncRNAs in the regulation of genes and signaling pathways through miRNA-mediated and other mechanisms in clear cell renal cell carcinoma
EA Braga, MV Fridman, EA Filippova… - International journal of …, 2021 - mdpi.com
The fundamental novelty in the pathogenesis of renal cell carcinoma (RCC) was discovered
as a result of the recent identification of the role of long non-coding RNAs (lncRNAs). Here, …
as a result of the recent identification of the role of long non-coding RNAs (lncRNAs). Here, …
[HTML][HTML] Aberrant methylation of 20 miRNA genes specifically involved in various steps of ovarian carcinoma spread: from primary tumors to peritoneal macroscopic …
VI Loginov, IV Pronina, EA Filippova… - International Journal of …, 2022 - mdpi.com
Our work aimed to differentiate 20 aberrantly methylated miRNA genes that participate at
different stages of development and metastasis of ovarian carcinoma (OvCa) using methylation-…
different stages of development and metastasis of ovarian carcinoma (OvCa) using methylation-…
[HTML][HTML] Safety and efficacy of p62 DNA vaccine ELENAGEN in a first-in-human trial in patients with advanced solid tumors
…, II Badrtdinova, BN Oshchepkov, EV Filippova… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Elenagen is a plasmid encoding p62/SQSTM1, the first DNA vaccine possessing two
mutually complementing mechanisms of action: it elicits immune response against p62 and …
mutually complementing mechanisms of action: it elicits immune response against p62 and …
[HTML][HTML] Dysregulation of lncRNA–miRNA–mRNA interactome as a marker of metastatic process in ovarian cancer
…, AA Moskovtsev, DM Zaichenko, EA Filippova… - Biomedicines, 2022 - mdpi.com
Ovarian cancer (OC) is one of the most common types of cancer among malignancies of the
female reproductive system. This pathology is asymptomatic until advanced stages and has …
female reproductive system. This pathology is asymptomatic until advanced stages and has …