User profiles for Elena WY Hsieh
 | Elena WY HsiehAssistant Professor, Immunology and Microbiology Verified email at cuanschutz.edu Cited by 2753 |
COVID-19: pandemic contingency planning for the allergy and immunology clinic
In the event of a global infectious pandemic, drastic measures may be needed that limit or
require adjustment of ambulatory allergy services. However, no rationale for how to prioritize …
require adjustment of ambulatory allergy services. However, no rationale for how to prioritize …
[HTML][HTML] Minimizing batch effects in mass cytometry data
Cytometry by Time-Of-Flight (CyTOF) uses antibodies conjugated to isotopically pure metals
to identify and quantify a large number of cellular features with single-cell resolution. A …
to identify and quantify a large number of cellular features with single-cell resolution. A …
Use of genetic testing for primary immunodeficiency patients
…, JW Verbsky, RL Wasserman, EWY Hsieh… - Journal of clinical …, 2018 - Springer
Genetic testing plays a critical role in diagnosis for many primary immunodeficiency diseases.
The goals of this report are to outline some of the challenges that clinical immunologists …
The goals of this report are to outline some of the challenges that clinical immunologists …
Highly multiplexed simultaneous detection of RNAs and proteins in single cells
To enable the detection of expression signatures specific to individual cells, we developed
PLAYR (proximity ligation assay for RNA), a method for highly multiplexed transcript …
PLAYR (proximity ligation assay for RNA), a method for highly multiplexed transcript …
Specialized interferon action in COVID-19
The impacts of interferon (IFN) signaling on COVID-19 pathology are multiple, with both
protective and harmful effects being documented. We report here a multiomics investigation of …
protective and harmful effects being documented. We report here a multiomics investigation of …
Exosome isolation by ultracentrifugation and precipitation and techniques for downstream analyses
…, HJ Chial, M Königshoff, EWY Hsieh… - Current Protocols in …, 2020 - Wiley Online Library
Exosomes are 50‐ to 150‐nm‐diameter extracellular vesicles secreted by all mammalian
cells except mature red blood cells and contribute to diverse physiological and pathological …
cells except mature red blood cells and contribute to diverse physiological and pathological …
[HTML][HTML] A novel human IL2RB mutation results in T and NK cell–driven immune dysregulation
The pleiotropic actions of interleukin-2 (IL-2) are essential for regulation of immune responses
and maintenance of immune tolerance. The IL-2 receptor (IL-2R) is composed of IL-2Rα, IL…
and maintenance of immune tolerance. The IL-2 receptor (IL-2R) is composed of IL-2Rα, IL…
Seroconversion stages COVID19 into distinct pathophysiological states
COVID19 is a heterogeneous medical condition involving diverse underlying
pathophysiological processes including hyperinflammation, endothelial damage, thrombotic …
pathophysiological processes including hyperinflammation, endothelial damage, thrombotic …
T and B cell abnormalities, pneumocystis pneumonia, and chronic lymphocytic leukemia associated with an AIOLOS defect in patients
…, B Boast, RM Baxter, EWY Hsieh… - Journal of Experimental …, 2021 - rupress.org
AIOLOS/IKZF3 is a member of the IKAROS family of transcription factors. IKAROS/IKZF1
mutations have been previously associated with different forms of primary immunodeficiency. …
mutations have been previously associated with different forms of primary immunodeficiency. …
Impact of SARS-CoV-2 infection and COVID-19 on patients with inborn errors of immunity
Since the arrival of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in
December 2019, its characterization as a novel human pathogen, and the resulting coronavirus …
December 2019, its characterization as a novel human pathogen, and the resulting coronavirus …