User profiles for Elif Nihal Korkmaz

Elif Nihal Korkmaz

Moderna
Verified email at modernatx.com
Cited by 232

[HTML][HTML] De novo design of high-affinity binders of bioactive helical peptides

…, M Lamb, SR Gerben, A Murray, P Heine, EN Korkmaz… - Nature, 2024 - nature.com
Many peptide hormones form an α-helix on binding their receptors 1 , 2 , 3 – 4 , and sensitive
methods for their detection could contribute to better clinical management of disease 5 . De …

Identification of the Ah-receptor structural determinants for ligand preferences

…, L Jiang, V Stanevich, EN Korkmaz… - Toxicological …, 2012 - academic.oup.com
The aryl hydrocarbon receptor (AHR) is a transcription factor that responds to diverse ligands
and plays a critical role in toxicology, immune function, and cardiovascular physiology. The …

Skip residues modulate the structural properties of the myosin rod and guide thick filament assembly

KC Taylor, M Buvoli, EN Korkmaz… - Proceedings of the …, 2015 - National Acad Sciences
The rod of sarcomeric myosins directs thick filament assembly and is characterized by the
insertion of four skip residues that introduce discontinuities in the coiled-coil heptad repeats. …

De novo design of high-affinity protein binders to bioactive helical peptides

…, GR Lee, PM Levine, X Li, M Lamb, EN Korkmaz… - Biorxiv, 2022 - biorxiv.org
Many peptide hormones form an alpha-helix upon binding their receptors 1 – 4 , and
sensitive detection methods for them could contribute to better clinical management. De novo …

[HTML][HTML] Conformational control of the binding of the transactivation domain of the MLL protein and c-Myb to the KIX domain of CREB

EN Korkmaz, R Nussinov… - PLoS computational …, 2012 - journals.plos.org
The KIX domain of CBP is a transcriptional coactivator. Concomitant binding to the activation
domain of proto-oncogene protein c-Myb and the transactivation domain of the trithorax …

Specificity landscapes unmask submaximal binding site preferences of transcription factors

…, J Pan, D Roston, EN Korkmaz… - Proceedings of the …, 2018 - National Acad Sciences
We have developed Differential Specificity and Energy Landscape (DiSEL) analysis to
comprehensively compare DNA–protein interactomes (DPIs) obtained by high-throughput …

Interplay of electrostatics and hydrophobic effects in the metamorphic protein human lymphotactin

EN Korkmaz, BF Volkman, Q Cui - The Journal of Physical …, 2015 - ACS Publications
The human lymphotactin (hLtn) is a protein that features two native states both of which are
physiologically relevant: it is a monomer (hLtn10) at 10 C with 200 mM salt and a dimer (…

Tagging proteins: Sumoylation mechanism by molecular modeling and molecular dynamics simulations

EN Korkmaz - 2010 - acikbilim.yok.gov.tr
Sumoylation, the covalent attachment of SUMO (Small Ubiquitin Like Modifier)to target proteins
is a posttranslational modification that can alter intracellularlocalization, interactions with …

[PDF][PDF] Eğitim ve Bilim Dergisinde Liderlik Alanında Yapılmış Makalelerin İncelenmesi ve Değerlendirilmesi

…, ALİR YÜCE, NS DUMAN, N KORKMAZ… - SOCIAL SCIENCES …, 2023 - sssjournal.com
Bu çalışmada Eğitim ve Bilim dergisinde Liderlik ile ilgili yapılmış makalelerin analiz edilmesi
amaçlanmıştır. Bu amaç doğrultusunda, Liderlik konusu ile ilgili makalelere ulaşmak …

Elektif sezaryen olan hastalarda post-operatif ağrı ve anksiyetenin azaltılmasında refleksolojinin etkisi

E Korkmaz Güven - 2017 - acikerisim.medipol.edu.tr
Ağrı ve anksiyete sezaryen sonrası kadınlarda sıklıkla görülen bir yakınma olup farmakolojik
ağrı kesici kullanımının artışında önemli bir etkiye sahiptir. Ancak son yıllarda ilaçların yan …