User profiles for Elijah S. Lawrence
Elijah S LawrenceDuke University School of Medicine - Medical Scientist Training Program (MD-PhD) Student Verified email at duke.edu Cited by 553 |
[HTML][HTML] Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission
…, ES Cresini, ER Eisner, AL Lastrella, ES Lawrence… - Nature, 2022 - nature.com
As SARS-CoV-2 continues to spread and evolve, detecting emerging variants early is critical
for public health interventions. Inferring lineage prevalence by clinical testing is infeasible …
for public health interventions. Inferring lineage prevalence by clinical testing is infeasible …
Functional EPAS1/HIF2A missense variant is associated with hematocrit in Andean highlanders
ES Lawrence, W Gu, RJ Bohlender… - Science …, 2024 - science.org
Hypoxia-inducible factor pathway genes are linked to adaptation in both human and
nonhuman highland species. EPAS1, a notable target of hypoxia adaptation, is associated with …
nonhuman highland species. EPAS1, a notable target of hypoxia adaptation, is associated with …
[HTML][HTML] Time domains of hypoxia responses and-omics insights
The ability to respond rapidly to changes in oxygen tension is critical for many forms of life.
Challenges to oxygen homeostasis, specifically in the contexts of evolutionary biology and …
Challenges to oxygen homeostasis, specifically in the contexts of evolutionary biology and …
[HTML][HTML] Safer at school early alert: an observational study of wastewater and surface monitoring to detect COVID-19 in elementary schools
…, C Hobbs, AL Lastrella, ES Lawrence… - The Lancet Regional …, 2023 - thelancet.com
Background Schools are high-risk settings for SARS-CoV-2 transmission, but necessary for
children's educational and social-emotional wellbeing. Previous research suggests that …
children's educational and social-emotional wellbeing. Previous research suggests that …
Genetic variants at the EGLN1 locus associated with high‐altitude adaptation in Tibetans are absent or found at low frequency in highland Andeans
EC Heinrich, L Wu, ES Lawrence… - Annals of Human …, 2019 - Wiley Online Library
EGLN1 encodes the hypoxia‐inducible factor (HIF) pathway prolyl hydroxylase 2 (PHD2)
that serves as an oxygen‐sensitive regulator of HIF activity. The EGLN1 locus exhibits a …
that serves as an oxygen‐sensitive regulator of HIF activity. The EGLN1 locus exhibits a …
Combined intermittent and sustained hypoxia is a novel and deleterious cardio-metabolic phenotype
Study Objectives Chronic obstructive pulmonary disease and obstructive sleep apnea overlap
syndrome is associated with excess mortality, and outcomes are related to the degree of …
syndrome is associated with excess mortality, and outcomes are related to the degree of …
Analysis of SARS-CoV-2 RNA persistence across indoor surface materials reveals best practices for environmental monitoring programs
Environmental monitoring in public spaces can be used to identify surfaces contaminated
by persons with coronavirus disease 2019 (COVID-19) and inform appropriate infection …
by persons with coronavirus disease 2019 (COVID-19) and inform appropriate infection …
SARS-CoV-2 Distribution in Residential Housing Suggests Contact Deposition and Correlates with Rothia sp.
…, A Hakim, L Kohn, AL Lastrella, ES Lawrence… - Msystems, 2022 - Am Soc Microbiol
Monitoring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on surfaces is
emerging as an important tool for identifying past exposure to individuals shedding viral RNA. …
emerging as an important tool for identifying past exposure to individuals shedding viral RNA. …
Genomic surveillance reveals dynamic shifts in the connectivity of COVID-19 epidemics
…, J Wilson, SN Ngo, A Plascencia, ES Lawrence… - Cell, 2023 - cell.com
The maturation of genomic surveillance in the past decade has enabled tracking of the
emergence and spread of epidemics at an unprecedented level. During the COVID-19 pandemic, …
emergence and spread of epidemics at an unprecedented level. During the COVID-19 pandemic, …
[HTML][HTML] Seq-ing higher ground: functional investigation of adaptive variation associated with high-altitude adaptation
Human populations at high altitude exhibit both unique physiological responses and strong
genetic signatures of selection thought to compensate for the decreased availability of …
genetic signatures of selection thought to compensate for the decreased availability of …