The development of biological markers of aging has primarily focused on adult samples.
Epigenetic clocks are a promising tool for measuring biological age that show impressive …

Epigenetic processes, including DNA methylation (DNAm), are among the mechanisms
allowing integration of genetic and environmental factors to shape cellular function. While many …

Background The fetal origins of mental health is a well-established framework that currently
lacks a robust index of the biological embedding of prenatal adversity. The Pediatric-Buccal-…

Background Activation of brain insulin receptors modulates reward sensitivity, inhibitory
control and memory. Variations in the functioning of this mechanism likely associate with …

Prenatal adversity shapes child neurodevelopment and risk for later mental health problems.
The quality of the early care environment can buffer some of the negative effects of prenatal …

While high doses of estrogen, in combination with androgens, can initiate prostate cancer (PCa)
via activation of the estrogen receptor α (ERα), the role of ERα in PCa cells within …

Background Polygenic risk scores (PRS) describe the genomic contribution to complex
phenotypes and consistently account for a larger proportion of variance in outcome than single …

Maternal behavior (MB) is observable across mammals and represents an important feature
of environmental variation during early postnatal development. Oxytocin (OT) plays a crucial …

… d , Elika Garg d , Bruna Regis Razzolini d e , Dawn Xin Ping Koh i , Heather Gallant g ,
Roberto Britto Sassi h , Geoffrey BC Hall g , Kieran John O’Donnell d f , Michael J. Meaney d e f i , …

Childhood psychiatric symptoms may be associated with advanced biological aging. This
study examined whether epigenetic age acceleration (EAA) associates with internalizing and …