Background: The prognostic significance of disseminated tumor cells (DTC) in bone marrow
(BM) of breast cancer patients at the time of primary diagnosis has been confirmed by a …

Background We conducted a meta-analysis in nonmetastatic breast cancer patients treated
by neoadjuvant chemotherapy (NCT) to assess the clinical validity of circulating tumor cell (…

Numerous single‐institutional studies and a large pooled analysis have demonstrated that
the presence of disseminated tumor cells (DTCs) in the bone marrow (BM) from patients with …

In the preceding decades, molecular characterization has revolutionized breast cancer (BC)
research and therapeutic approaches. Presented herein, an unbiased analysis of breast …

How mixtures of immune cells associate with cancer cell phenotype and affect pathogenesis
is still unclear. In 15 breast cancer gene expression datasets, we invariably identify three …

Purpose: The aim of the study was to explore the value of analyzing bone marrow (BM) for
the presence of isolated tumor cell(s) (ITCs) in disease-free breast cancer patients 3 years …

Distinct molecular subtypes of breast carcinomas have been identified, but translation into
clinical use has been limited. We have developed two platform-independent algorithms to …

Expression profiles of primary breast tumors were investigated in relation to disseminated
tumor cells (DTCs) in bone marrow (BM) in order to increase our understanding of the …

Background The aim of this study was to investigate the prognostic value of the PAM50 intrinsic
subtypes and risk of recurrence (ROR) score in patients with early breast cancer and long…

Breast cancers exhibit genome-wide aberrant DNA methylation patterns. To investigate how
these affect the transcriptome and which changes are linked to transformation or …