User profiles for Elisa E Konofagou

Elisa E. Konofagou

Verified email at columbia.edu
Cited by 21040

Noninvasive, transcranial and localized opening of the blood-brain barrier using focused ultrasound in mice

JJ Choi, M Pernot, SA Small, EE Konofagou - Ultrasound in medicine & …, 2007 - Elsevier
The feasibility of blood-brain barrier (BBB) opening in the hippocampus of wild-type mice
using focused ultrasound (FUS) through the intact skull and skin was investigated. Needle …

Elastography: Imaging the elastic properties of soft tissues with ultrasound

…, SK Alam, BS Garra, F Kallel, EE Konofagou… - Journal of medical …, 2002 - Springer
Elastography is a method that can ultimately generate several new kinds of images, called
elastograms. As such, all the properties of elastograms are different from the familiar …

[HTML][HTML] Reduced thoracolumbar fascia shear strain in human chronic low back pain

…, NA Bouffard, EE Konofagou… - BMC musculoskeletal …, 2011 - Springer
Background The role played by the thoracolumbar fascia in chronic low back pain (LBP) is
poorly understood. The thoracolumbar fascia is composed of dense connective tissue layers …

Myocardial elastography—A feasibility study in vivo

EE Konofagou, J D'hooge, J Ophir - Ultrasound in medicine & biology, 2002 - Elsevier
Early detection of cardiovascular diseases has been a very active research area in the
medical imaging field. Assessment of the local and global mechanical functions is one of the …

Localized harmonic motion imaging: theory, simulations and experiments

EE Konofagou, K Hynynen - Ultrasound in medicine & biology, 2003 - Elsevier
Several techniques have been developed in an effort to estimate mechanical properties of
tissues. These techniques typically estimate static or harmonic motion resulting from an …

A fast normalized cross-correlation calculation method for motion estimation

J Luo, EE Konofagou - IEEE transactions on ultrasonics …, 2010 - ieeexplore.ieee.org
High-precision motion estimation has become essential in ultrasound-based techniques such
as time-domain Doppler and elastography. Normalized cross-correlation (NCC) has been …

Microbubble-Size Dependence of Focused Ultrasound-Induced Blood–Brain Barrier Opening in Mice In Vivo

…, YS Tung, MA Borden, EE Konofagou - IEEE Transactions …, 2009 - ieeexplore.ieee.org
The therapeutic efficacy of neurological agents is severely limited, because large compounds
do not cross the blood-brain barrier (BBB). Focused ultrasound (FUS) sonication in the …

In vivo transcranial cavitation threshold detection during ultrasound-induced blood–brain barrier opening in mice

…, T Deffieux, K Selert, EE Konofagou - Physics in Medicine …, 2010 - iopscience.iop.org
The in vivo cavitation response associated with blood–brain barrier (BBB) opening as induced
by transcranial focused ultrasound (FUS) in conjunction with microbubbles was studied in …

The size of blood–brain barrier opening induced by focused ultrasound is dictated by the acoustic pressure

H Chen, EE Konofagou - Journal of Cerebral Blood Flow & …, 2014 - journals.sagepub.com
Focused ultrasound (FUS) in combination with microbubbles (MBs) has been successfully
used in the delivery of various-size therapeutic agents across the blood–brain barrier (BBB). …

An adaptive strain estimator for elastography

SK Alam, J Ophir, EE Konofagou - IEEE transactions on …, 1998 - ieeexplore.ieee.org
Elastography is based on the estimation of strain due to applied tissue compression. In
conventional elastography, strain is computed from the gradient of the displacement estimates …