How severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections engage
cellular host pathways and innate immunity in infected cells remains largely elusive. We …

Viruses hijack host metabolic pathways for their replicative advantage. In this study, using
patient-derived multiomics data and in vitro infection assays, we aimed to understand the role …

Emerging and re-emerging infectious diseases due to RNA viruses cause major negative
consequences for the quality of life, public health, and overall economic development. Most of …

The commonly used laboratory cell lines are the first line of experimental models to study the
pathogenicity and performing antiviral assays for emerging viruses. Here, we assessed the …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes Coronavirus
disease 2019 (COVID-19) has caused a global health emergency. A key feature of COVID-19 …

Most COVID-19 victims are old and die from unrelated causes. Here we present twelve
complete autopsies, including two rapid autopsies of young patients where the cause of death …

Despite the availability of several anti-retrovirals, there is still an urgent need for developing
novel therapeutic strategies and finding new drugs against underexplored HIV-1 targets. …

In one year of the coronavirus disease 2019 (COVID-19) pandemic, many studies have
described the different metabolic changes occurring in COVID-19 patients, linking these …

Viruses hijack host metabolic pathways for their replicative advantage. Several observational
trans-omics analyses associated carbon and amino acid metabolism in coronavirus …

Untreated HIV-1 infection leads to a slow decrease in CD4 + T cell lymphocytes over time
resulting in increased susceptibility to opportunistic infections (acquired immunodeficiency …