[HTML][HTML] Snail is a direct target of hypoxia-inducible factor 1α (HIF1α) in hypoxia-induced endothelial to mesenchymal transition of human coronary endothelial cells
X Xu, X Tan, B Tampe, E Sanchez, M Zeisberg… - Journal of Biological …, 2015 - ASBMB
Endothelial to mesenchymal transition (EndMT) was originally described in heart development
where the endocardial endothelial cells that line the atrioventricular canal undergo an …
where the endocardial endothelial cells that line the atrioventricular canal undergo an …
[PDF][PDF] Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer
Immune cells identify and destroy tumors by recognizing cellular traits indicative of oncogenic
transformation. In this study, we found that myocardin-related transcription factors (MRTFs)…
transformation. In this study, we found that myocardin-related transcription factors (MRTFs)…
[HTML][HTML] Mechanically active integrins target lytic secretion at the immune synapse to facilitate cellular cytotoxicity
Cytotoxic lymphocytes fight pathogens and cancer by forming immune synapses with infected
or transformed target cells and then secreting cytotoxic perforin and granzyme into the …
or transformed target cells and then secreting cytotoxic perforin and granzyme into the …
Fish melanocortin system
…, MJ Agulleiro, R Guillot, E Sánchez… - European journal of …, 2011 - Elsevier
Melanocortin signalling is mediated by binding to a family of G protein-coupled receptors
that positively couple to adenylyl cyclase. Tetrapod species have five melanocortin (MC 1 –MC …
that positively couple to adenylyl cyclase. Tetrapod species have five melanocortin (MC 1 –MC …
Expression of long-chain polyunsaturated fatty acid (LC-PUFA) biosynthesis genes during zebrafish Danio rerio early embryogenesis
Ó Monroig, J Rotllant, E Sánchez… - … et Biophysica Acta (BBA …, 2009 - Elsevier
Long-chain polyunsaturated fatty acids (LC-PUFAs) are essential in important physiological
processes, many of which are particularly vital during embryonic development. This study …
processes, many of which are particularly vital during embryonic development. This study …
[HTML][HTML] Physical stability studies of semi-solid formulations from natural compounds loaded with chitosan microspheres
A chitosan-based hydrophilic system containing an olive leaf extract was designed and its
antioxidant capacity was evaluated. Encapsulation of olive leaf extract in chitosan …
antioxidant capacity was evaluated. Encapsulation of olive leaf extract in chitosan …
Apoptotic contraction drives target cell release by cytotoxic T cells
EE Sanchez, M Tello-Lafoz, AJ Guo, M de Jesus… - Nature …, 2023 - nature.com
Cytotoxic T lymphocytes (CTLs) fight intracellular pathogens and cancer by identifying and
destroying infected or transformed target cells 1 . To kill, CTLs form a specialized cytotoxic …
destroying infected or transformed target cells 1 . To kill, CTLs form a specialized cytotoxic …
Role of melanocortin receptor accessory proteins in the function of zebrafish melanocortin receptor type 2
MJ Agulleiro, S Roy, E Sánchez, S Puchol… - Molecular and Cellular …, 2010 - Elsevier
In this paper, we identify three different MRAPs in zebrafish, zfMRAP1, zfMRAP2a and
zfMRAP2b, and demonstrate that zfMC2R is not functional in the absence of MRAP expression. …
zfMRAP2b, and demonstrate that zfMC2R is not functional in the absence of MRAP expression. …
[HTML][HTML] A linear DNA encoding the SARS-CoV-2 receptor binding domain elicits potent immune response and neutralizing antibodies in domestic cats
A Conforti, E Sanchez, E Salvatori, L Lione… - … Therapy Methods & …, 2023 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiologic agent of the
COVID-19 pandemic, has been shown to infect a wide range of animal species, especially …
COVID-19 pandemic, has been shown to infect a wide range of animal species, especially …
Phosphodiesterase inhibitor-dependent inverse agonism of agouti-related protein on melanocortin 4 receptor in sea bass (Dicentrarchus labrax)
E Sánchez, VC Rubio, D Thompson… - American Journal …, 2009 - journals.physiology.org
The melanocortin 4 receptor (MC4R) is a G protein-coupled receptor mainly expressed in the
central nervous system of vertebrates. Activation of the MC4R leads to a decrease in food …
central nervous system of vertebrates. Activation of the MC4R leads to a decrease in food …