[HTML][HTML] The Delta SARS-CoV-2 variant has a higher viral load than the Beta and the historical variants in nasopharyngeal samples from newly diagnosed COVID-19 …

E Teyssou, H Delagrèverie, B Visseaux… - The Journal of …, 2021 - ncbi.nlm.nih.gov
Following the publication of Tang et al. 1, we have previously shown that the Beta variant
presented an intermediate relative viral load (VL) between the Alpha and the historical …

Mutations in SQSTM1 encoding p62 in amyotrophic lateral sclerosis: genetics and neuropathology

E Teyssou, T Takeda, V Lebon, S Boillée… - Acta …, 2013 - Springer
Mutations in SQSTM1 encoding the sequestosome 1/p62 protein have recently been identified
in familial and sporadic cases of amyotrophic lateral sclerosis (ALS). p62 is a component …

Phenotype difference between ALS patients with expanded repeats in C9ORF72 and patients with mutations in other ALS-related genes

…, S Boillée, I Le Ber, D Seilhean, E Teyssou… - Journal of medical …, 2012 - jmg.bmj.com
Background Expanded GGGGCC hexanucleotide repeats in the promoter of the C9ORF72
gene have recently been identified in frontotemporal dementia (FTD), Amyotrophic Lateral …

[HTML][HTML] Evolution of viral quasispecies during SARS-CoV-2 infection

…, I Malet, S Marot, E Klement-Frutos, E Teyssou… - Clinical Microbiology …, 2020 - Elsevier
Objectives Studies are needed to better understand the genomic evolution of the recently
emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This study aimed to …

[HTML][HTML] Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis

…, JF Passos, J Attems, EA Veal, E Teyssou… - Nature …, 2018 - nature.com
Cellular homoeostatic pathways such as macroautophagy (hereinafter autophagy) are regulated
by basic mechanisms that are conserved throughout the eukaryotic kingdom. However, …

[HTML][HTML] Co-infection of SARS-CoV-2 with other respiratory viruses and performance of lower respiratory tract samples for the diagnosis of COVID-19

…, M Dres, V Pourcher, CE Luyt, E Teyssou… - International Journal of …, 2021 - Elsevier
Objectives We performed a study during the early outbreak period of coronavirus disease
2019 (COVID-19) and the seasonal epidemics of other respiratory viral infections in order to …

Transmitted drug resistance to integrase-based first-line human immunodeficiency virus antiretroviral regimens in Mediterranean Europe

…, L Viñuela, A Fuentes, E Teyssou… - Clinical Infectious …, 2023 - academic.oup.com
Background We evaluated the prevalence of transmitted drug resistance (TDR) to integrase
strand-transfer inhibitors (INSTIs) and nucleoside/nucleotide reverse transcriptase inhibitors (…

Novel UBQLN2 mutations linked to amyotrophic lateral sclerosis and atypical hereditary spastic paraplegia phenotype through defective HSP70-mediated proteolysis

E Teyssou, L Chartier, R Lam, G Lautrette, M Nicol… - Neurobiology of …, 2017 - Elsevier
Mutations in UBQLN2 have been associated with rare cases of X-linked juvenile and adult
forms of amyotrophic lateral sclerosis (ALS) and ALS linked to frontotemporal dementia (FTD). …

[HTML][HTML] Virological efficacy of switch to DTG plus 3TC in a retrospective observational cohort of suppressed HIV-1 patients with or without past M184V: the LAMRES …

MM Santoro, D Armenia, E Teyssou, JR Santos… - Journal of Global …, 2022 - Elsevier
Objectives The aim of this study was to assess the efficacy of dolutegravir plus lamivudine (DTG+3TC)
in a large set of virologically suppressed HIV-1 infected individuals with or without …

[HTML][HTML] The amyotrophic lateral sclerosis M114T PFN1 mutation deregulates alternative autophagy pathways and mitochondrial homeostasis

E Teyssou, L Chartier, D Roussel, ND Perera… - International Journal of …, 2022 - mdpi.com
Mutations in profilin 1 (PFN1) have been identified in rare familial cases of Amyotrophic
Lateral Sclerosis (ALS). PFN1 is involved in multiple pathways that could intervene in ALS …