Inhibition of the cell-cycle kinases CDK4 and CDK6 is now part of the standard treatment in
advanced breast cancer. CDK4/6 inhibitors, however, are not expected to cooperate with …

PP2A is a major tumor suppressor whose inactivation is frequently found in a wide spectrum
of human tumors. In particular, deletion or epigenetic silencing of genes encoding the B55 …

Full differentiation potential along with self‐renewal capacity is a major property of pluripotent
stem cells (PSCs). However, the differentiation capacity frequently decreases during …

Background Kindler Syndrome (KS) is an autosomal recessive skin disorder characterized
by skin blistering, photosensitivity, premature aging, and propensity to skin cancer. In spite of …

Full differentiation potential along with self‐renewal capacity is a major property of pluripotent
stem cells (PSCs). However, the differentiation capacity frequently decreases during …

2307: Sequential treatment with abemaciclib plus endocrine therapy inhibits cell proliferation
and triggers apoptosis in cell lines resistant to CDK4/6i | Cancer Research | American …

Full differentiation potential along with self-renewal capacity is a major property of pluripotent
stem cells (PSCs). However, the differentiation capacity frequently decreases during …

The formidable protective barrier function of the skin can be subverted by traumatic loss or
disease. Self-repair of small and moderate cutaneous damage is an efficient process which, …

Background The epidermis forms a critical barrier that is maintained by orchestrated programs
of proliferation, differentiation, and cell death. Gene mutations that disturb this turnover …

Translating Regenerative Medicine to the Clinic reviews the current methodological tools and
experimental approaches used by leading translational researchers, discussing the uses …