User profiles for Elisabeth C. Kugler
Elisabeth KuglerUCL Verified email at ucl.ac.uk Cited by 283 |
[HTML][HTML] The “neuro-glial-vascular” unit: the role of glia in neurovascular unit formation and dysfunction
EC Kugler, J Greenwood… - Frontiers in Cell and …, 2021 - frontiersin.org
The neurovascular unit (NVU) is a complex multi-cellular structure consisting of endothelial
cells (ECs), neurons, glia, smooth muscle cells (SMCs), and pericytes. Each component is …
cells (ECs), neurons, glia, smooth muscle cells (SMCs), and pericytes. Each component is …
Zebrafish vascular quantification: a tool for quantification of three-dimensional zebrafish cerebrovascular architecture by automated image analysis
EC Kugler, J Frost, V Silva, K Plant… - …, 2022 - journals.biologists.com
Zebrafish transgenic lines and light sheet fluorescence microscopy allow in-depth insights
into three-dimensional vascular development in vivo. However, quantification of the zebrafish …
into three-dimensional vascular development in vivo. However, quantification of the zebrafish …
Cerebrovascular endothelial cells form transient Notch‐dependent cystic structures in zebrafish
We identify a novel endothelial membrane behaviour in transgenic zebrafish. Cerebral blood
vessels extrude large transient spherical structures that persist for an average of 23 min …
vessels extrude large transient spherical structures that persist for an average of 23 min …
[HTML][HTML] Cerebrovascular development: mechanisms and experimental approaches
The cerebral vasculature plays a central role in human health and disease and possesses
several unique anatomic, functional and molecular characteristics. Despite their importance, …
several unique anatomic, functional and molecular characteristics. Despite their importance, …
Therapeutic targeting of vascular malformation in a zebrafish model of hereditary haemorrhagic telangiectasia
…, K Plant, EC Kugler, C Doh… - Disease Models & …, 2023 - journals.biologists.com
Hereditary haemorrhagic telangiectasia (HHT) causes arteriovenous malformations (AVMs)
in multiple organs to cause bleeding, neurological and other complications. HHT is caused …
in multiple organs to cause bleeding, neurological and other complications. HHT is caused …
Segmentation of the zebrafish brain vasculature from light sheet fluorescence microscopy datasets
Light sheet fluorescent microscopy allows imaging of zebrafish vascular development in great
detail. However, interpretation of data often relies on visual assessment and approaches …
detail. However, interpretation of data often relies on visual assessment and approaches …
[HTML][HTML] Meeting in the middle: towards successful multidisciplinary bioimage analysis collaboration
With an increase in subject knowledge expertise required to solve specific biological questions,
experts from different fields need to collaborate to address increasingly complex issues. …
experts from different fields need to collaborate to address increasingly complex issues. …
Analytical Approaches for the Segmentation of the Zebrafish Brain Vasculature
With advancements in imaging techniques, data visualization allows new insights into
fundamental biological processes of development and disease. However, although biomedical …
fundamental biological processes of development and disease. However, although biomedical …
TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome
…, H Kett, M Habdank, CM Kugler… - Blood, The Journal …, 2012 - ashpublications.org
To assess the frequency of TP53 alterations and their correlation with other genetic changes
and outcome in acute myeloid leukemia with complex karyotype (CK-AML), we performed …
and outcome in acute myeloid leukemia with complex karyotype (CK-AML), we performed …
Introducing garmi-a service robotics platform to support the elderly at home: Design philosophy, system overview and first results
…, B Loinger, T Loibl, C Kugler, C Calafell… - IEEE Robotics and …, 2021 - ieeexplore.ieee.org
This letter introduces GARMI, a service robotics platform conceptualized with a focus on
assisting elderly at home. GARMI is designed to provide support with household tasks, as an …
assisting elderly at home. GARMI is designed to provide support with household tasks, as an …