SARS-CoV-2 infection poses a major threat to the lungs and multiple other organs,
occasionally causing death. Until effective vaccines are developed to curb the pandemic, it is …

Extracellular chromatin, for example in the form of neutrophil extracellular traps (NETs), is an
important element that propels the pathological progression of a plethora of diseases. DNA …

Gout is characterized by an acute inflammatory reaction and the accumulation of neutrophils
in response to monosodium urate (MSU) crystals. Inflammation resolves spontaneously …

Background Coronavirus induced disease 2019 (COVID-19) can be complicated by severe
organ damage leading to dysfunction of the lungs and other organs. The processes that …

The tumor immune microenvironment (TIME) controls tumorigenesis. Neutrophils are important
components of TIME and control tumor progression and therapy resistance. Neutrophil …

Kaposi's sarcoma–associated herpesvirus (KSHV) is the causative agent of Kaposi's sarcoma
1 , a highly vascularized tumor originating from lymphatic endothelial cells, and of at least …

During angiogenesis and inflammatory processes, endothelial cells acquire different
activation phenotypes, whose identification may help in understanding the complex network of …

Inflammatory bowel disease (IBD) is a chronic inflammatory disorder with rising incidence.
Diseased tissues are heavily vascularized. Surprisingly, the pathogenic impact of the …

Expression of the large GTPase guanylate binding protein‐1 (GBP‐1) is induced by
inflammatory cytokines (ICs) in endothelial cells (ECs), and the helical domain of the molecule …

Fibroblasts are polymorphic cells with pleiotropic roles in organ morphogenesis, tissue
homeostasis and immune responses. In fibrotic diseases, fibroblasts synthesize abundant …