It is well established that oxidative stress is an important cause of cell damage associated
with the initiation and progression of many diseases. Consequently, all air-living organisms …

The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU-ROS) …

Eukaryotic 2-Cys peroxiredoxins (Prx) are abundant antioxidant enzymes whose thioredoxin
peroxidase activity plays an important role in protecting against oxidative stress, aging, and …

Oxidative stress-induced cell damage is an important component of many diseases and
ageing. In eukaryotes, activation of JNK/p38 stress-activated protein kinase (SAPK) signaling …

We have identified three genes,gst1 + , gst2 + , andgst3 + , encoding θ-class glutathioneS-transferases
(GSTs) in Schizosaccharomyces pombe. The gst1 + andgst2 + genes encode …

Oxidative damage caused by reactive oxygen species (ROS) is implicated in many diseases
and in aging. Removal of ROS by antioxidant enzymes plays an important part in limiting …

We describe the characterization of Ybp1, a novel protein, in Saccharomyces cerevisiae,
that is required for the oxidative stress response to peroxides. Ybp1 is required for H 2 O 2 -…

Although activation of the AP-1-like transcription factor Pap1 in Schizosaccharomyces
pombe is important for oxidative stress-induced gene expression, this activation is delayed at …

Cellular homoeostatic pathways such as macroautophagy (hereinafter autophagy) are regulated
by basic mechanisms that are conserved throughout the eukaryotic kingdom. However, …

ROS (reactive oxygen species) are potentially damaging by-products of aerobic metabolism
which, unchecked, can have detrimental effects on cell function. However, it is now widely …