Domain-specific working memory, but not dopamine-related genetic variability, shapes reward-based motor learning
…, O Codol, E Oxley, M Taylor, E Hamshere… - Journal of …, 2019 - Soc Neuroscience
The addition of rewarding feedback to motor learning tasks has been shown to increase the
retention of learning, spurring interest in its possible utility for rehabilitation. However, motor …
retention of learning, spurring interest in its possible utility for rehabilitation. However, motor …
Genomewide linkage scan in schizoaffective disorder: significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13
ML Hamshere, P Bennett, N Williams… - Archives of general …, 2005 - jamanetwork.com
Context Traditionally, the search for genes involved in predisposition to major psychoses
has proceeded with separate studies of schizophrenia and bipolar disorder. However, twin …
has proceeded with separate studies of schizophrenia and bipolar disorder. However, twin …
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
Copy number variants (CNVs) have been strongly implicated in the genetic etiology of
schizophrenia (SCZ). However, genome-wide investigation of the contribution of CNV to risk has …
schizophrenia (SCZ). However, genome-wide investigation of the contribution of CNV to risk has …
Bipolar affective puerperal psychosis: genome-wide significant evidence for linkage to chromosome 16
I Jones, M Hamshere, JM Nangle… - American Journal of …, 2007 - Am Psychiatric Assoc
Objective: Vulnerability to the triggering of bipolar episodes by childbirth aggregates in families
and may define a genetically relevant subtype of bipolar disorder. The authors conducted …
and may define a genetically relevant subtype of bipolar disorder. The authors conducted …
[PDF][PDF] Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases
Regulatory and coding variants are known to be enriched with associations identified by
genome-wide association studies (GWASs) of complex disease, but their contributions to trait …
genome-wide association studies (GWASs) of complex disease, but their contributions to trait …
GWAS meta-analysis of suicide attempt: identification of 12 genome-wide significant loci and implication of genetic risks for specific health factors
…, J Guzman-Parra, ML Hamshere… - American journal of …, 2023 - Am Psychiatric Assoc
Objective: Suicidal behavior is heritable and is a major cause of death worldwide. Two large-scale
genome-wide association studies (GWASs) recently discovered and cross-validated …
genome-wide association studies (GWASs) recently discovered and cross-validated …
Mood‐incongruent psychosis in bipolar disorder: Conditional linkage analysis shows genome‐wide suggestive linkage at 1q32. 3, 7p13 and 20q13. 31
ML Hamshere, TG Schulze, J Schumacher… - Bipolar …, 2009 - Wiley Online Library
Objective: The majority of research into functional psychosis has proceeded under the
assumption that schizophrenia and bipolar disorder are distinct entities with separate underlying …
assumption that schizophrenia and bipolar disorder are distinct entities with separate underlying …
Sex-dependent shared and nonshared genetic architecture across mood and psychotic disorders
…, J Gratten, L de Haan, C Hammer, ML Hamshere… - Biological …, 2022 - Elsevier
Background Sex differences in incidence and/or presentation of schizophrenia (SCZ), major
depressive disorder (MDD), and bipolar disorder (BIP) are pervasive. Previous evidence for …
depressive disorder (MDD), and bipolar disorder (BIP) are pervasive. Previous evidence for …
A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts
…, J Gratten, L de Haan, C Hammer, ML Hamshere… - Biological …, 2021 - Elsevier
Background Polygenic scores (PGSs), which assess the genetic risk of individuals for a disease,
are calculated as a weighted count of risk alleles identified in genome-wide association …
are calculated as a weighted count of risk alleles identified in genome-wide association …
Operation of the schizophrenia susceptibility gene, neuregulin 1, across traditional diagnostic boundaries to increase risk for bipolar disorder
…, S Hyde, D Grozeva, M Hamshere… - Archives of general …, 2005 - jamanetwork.com
Context Family and twin data suggest that, in addition to susceptibility genes specific for
bipolar disorder or schizophrenia, genes exist that contribute to susceptibility across the …
bipolar disorder or schizophrenia, genes exist that contribute to susceptibility across the …