Background The functional modulation of blood flow in the brain is critical for brain health
and is the basis of contrast in functional magnetic resonance imaging. There is evident …

We report a three-dimensional microscopy technique—swept, confocally-aligned planar
excitation (SCAPE) microscopy—that allows volumetric imaging of living samples at ultrahigh …

Synaptic transmission initiates a cascade of signal transduction events that couple neuronal
activity to local changes in blood flow and oxygenation. Although a number of vasoactive …

The limited per-pixel bandwidth of most microscopy methods requires compromises between
field of view, sampling density and imaging speed. This limitation constrains studies …

For the first time, three-dimensional images of the newborn infant brain have been generated
using measurements of transmitted light. A 32-channel time-resolved imaging system was …

Although modern techniques such as two-photon microscopy can now provide cellular-level
three-dimensional imaging of the intact living brain, the speed and fields of view of these …

Functional magnetic resonance imaging (fMRI) provides a unique view of the working
human mind. The blood-oxygen-level-dependent (BOLD) signal, detected in fMRI, reflects …

Optical brain imaging has seen 30 years of intense development, and has grown into a rich
and diverse field. In-vivo imaging using light provides unprecedented sensitivity to functional …

The majority of retinoid (vitamin A and its metabolites) present in the body of a healthy
vertebrate is contained within lipid droplets present in the cytoplasm of hepatic stellate cells (HSCs…

The cortical hemodynamic response to somatosensory stimulus is investigated at the level
of individual vascular compartments using both depth-resolved optical imaging and in-vivo …