[PDF][PDF] Tumor-suppressor inactivation of GDF11 occurs by precursor sequestration in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is an aggressive and heterogeneous carcinoma in
which various tumor-suppressor genes are lost by mutation, deletion, or silencing. Here we …
which various tumor-suppressor genes are lost by mutation, deletion, or silencing. Here we …
[HTML][HTML] Computational models of reactive oxygen species as metabolic byproducts and signal-transduction modulators
EJ Pereira, CM Smolko, KA Janes - Frontiers in pharmacology, 2016 - frontiersin.org
Reactive oxygen species (ROS) are widely involved in intracellular signaling and human
pathologies, but their precise roles have been difficult to enumerate and integrate holistically. …
pathologies, but their precise roles have been difficult to enumerate and integrate holistically. …
Sporadic activation of an oxidative stress–dependent NRF2-p53 signaling network in breast epithelial spheroids and premalignancies
EJ Pereira, JS Burns, CY Lee, T Marohl, D Calderon… - Science …, 2020 - science.org
Breast and mammary epithelial cells experience different local environments during tissue
development and tumorigenesis. Microenvironmental heterogeneity gives rise to distinct cell …
development and tumorigenesis. Microenvironmental heterogeneity gives rise to distinct cell …
[HTML][HTML] Global assessment of marine plastic exposure risk for oceanic birds
Plastic pollution is distributed patchily around the world’s oceans. Likewise, marine
organisms that are vulnerable to plastic ingestion or entanglement have uneven distributions. …
organisms that are vulnerable to plastic ingestion or entanglement have uneven distributions. …
Mammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function
AL Pereira, AJ Pereira, ARR Maia… - Molecular biology of …, 2006 - Am Soc Cell Biol
CLASPs are widely conserved microtubule plus-end–tracking proteins with essential roles
in the local regulation of microtubule dynamics. In yeast, Drosophila, and Xenopus, a single …
in the local regulation of microtubule dynamics. In yeast, Drosophila, and Xenopus, a single …
[HTML][HTML] Zika virus infection in pregnant women in Rio de Janeiro
P Brasil, JP Pereira Jr, ME Moreira… - … England Journal of …, 2016 - Mass Medical Soc
Background Zika virus (ZIKV) has been linked to central nervous system malformations in
fetuses. To characterize the spectrum of ZIKV disease in pregnant women and infants, we …
fetuses. To characterize the spectrum of ZIKV disease in pregnant women and infants, we …
Salivary protein and solCD44 levels as a potential screening tool for early detection of head and neck squamous cell carcinoma
EJ Franzmann, EP Reategui, LHM Pereira… - Head & …, 2012 - Wiley Online Library
Background Head and neck squamous cell carcinoma (HNSCC) is a devastating disease
usually diagnosed at a late stage when cure rates are 40%. We examined a simple and …
usually diagnosed at a late stage when cure rates are 40%. We examined a simple and …
Randomized phase III trial of pemetrexed versus docetaxel in patients with non–small-cell lung cancer previously treated with chemotherapy
…, JR Pereira, F De Marinis, J Von Pawel… - Journal of clinical …, 2004 - ascopubs.org
Purpose To compare the efficacy and toxicity of pemetrexed versus docetaxel in patients
with advanced non—small-cell lung cancer (NSCLC) previously treated with chemotherapy. …
with advanced non—small-cell lung cancer (NSCLC) previously treated with chemotherapy. …
An update to the systematic literature review of empirical evidence of the impacts and outcomes of computer games and serious games
Continuing interest in digital games indicated that it would be useful to update Connolly et al.'s
(2012) systematic literature review of empirical evidence about the positive impacts and …
(2012) systematic literature review of empirical evidence about the positive impacts and …
Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled …
…, P Parikh, JR Pereira, T Ciuleanu, J Von Pawel… - The Lancet, 2005 - thelancet.com
Background This placebo-controlled phase III study investigated the effect on survival of
gefitinib as second-line or third-line treatment for patients with locally advanced or metastatic …
gefitinib as second-line or third-line treatment for patients with locally advanced or metastatic …