The compartmentalization of the cerebellum into modules is often used to discuss its function.
What, exactly, can be considered a module, how do they operate, can they be subdivided …

We hypothesized that early-life gut microbiota support the functional organization of neural
circuitry in the brain via regulation of synaptic gene expression and modulation of microglial …

Polyglutamine (polyQ) diseases are caused by expansion of translated CAG repeats in distinct
genes leading to altered protein function. In spinocerebellar ataxia type 1 (SCA1), a gain …

Purkinje cells receive synaptic input from several classes of interneurons. Here, we address
the roles of inhibitory molecular layer interneurons in establishing Purkinje cell function in …

Preterm infants that suffer cerebellar insults often develop motor disorders and cognitive
difficulty. Excitatory granule cells, the most numerous neuron type in the brain, are especially …

The cerebellum is the focus of an emergent series of debates because its circuitry is now
thought to encode an unexpected level of functional diversity. The flexibility that is built into the …

Ramón y Cajal proclaimed the neuron doctrine based on circuit features he exemplified
using cerebellar basket cell projections. Basket cells form dense inhibitory plexuses that wrap …

The brain contains a large diversity of unique cell types that use specific genetic programs
to control development and instruct the intricate wiring of sensory, motor, and cognitive brain …

Anatomical labeling approaches are essential for understanding brain organization. Among
these approaches are various methods of performing tract tracing. However, a major hurdle …

The cerebellar cortex contributes to diverse behaviors by transforming mossy fiber inputs into
predictions in the form of Purkinje cell (PC) outputs, and then refining those predictions 1. …