The human endogenous intestinal microflora is an essential “organ” in providing nourishment,
regulating epithelial development, and instructing innate immunity; yet, surprisingly, basic …

The Cancer Genome Atlas Network recently cataloged recurrent genomic abnormalities in
glioblastoma multiforme (GBM). We describe a robust gene expression-based molecular …

High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful
new tools for investigating a wide range of biological and medical questions. Statistical …

Background Single-cell transcriptomics allows researchers to investigate complex communities
of heterogeneous cells. It can be applied to stem cells and their descendants in order to …

The microbiota of the human stomach and the influence of Helicobacter pylori colonization
on its composition remain largely unknown. We characterized bacterial diversity within the …

Altered olfactory function is a common symptom of COVID-19, but its etiology is unknown. A
key question is whether SARS-CoV-2 (CoV-2) – the causal agent in COVID-19 – affects …

Breast cancers are comprised of molecularly distinct subtypes that may respond differently to
pathway-targeted therapies now under development. Collections of breast cancer cell lines …

Root endophytes have been shown to have important roles in determining host fitness under
periods of drought stress, and yet the effect of drought on the broader root endosphere …

Plant response to drought stress involves fungi and bacteria that live on and in plants and in
the rhizosphere, yet the stability of these myco- and micro-biomes remains poorly …

Recent studies have demonstrated that drought leads to dramatic, highly conserved shifts in
the root microbiome. At present, the molecular mechanisms underlying these responses …