Parkinson's disease is characterized by the presence of intracellular aggregates composed
primarily of the neuronal protein α-synuclein (αS). Interactions between αS and various …

Recent theoretical work suggests that protein folding involves an ensemble of pathways on a
rugged energy landscape. We provide direct evidence for heterogeneous folding pathways …

α-Synuclein (αS) is a soluble synaptic protein that is the major proteinaceous component of
insoluble fibrillar Lewy body deposits that are the hallmark of Parkinson's disease. The …

Analysis of infected macrophages revealed that lipid‐containing moieties of the mycobacterial
cell wall are actively trafficked out of the mycobacterial vacuole. To facilitate the analysis …

Mycobacterium abscessus is an increasingly important cause of human disease; however,
virulence determinants are largely uncharacterized. Previously, it was demonstrated that a …

PurPose—To establish what is currently known about factors that affect foreign language
listening comprehension, with a focus on characteristics of the listener, passage, and testing …

Interactions between the synaptic protein α-Synuclein and cellular membranes may be
relevant both to its native function as well as its role in Parkinson’s disease. We use single …

The hallmark of Mycobacterium-induced pathology is granulomatous inflammation at the
site of infection. Mycobacterial lipids are potent immunomodulators that contribute to the …

Pathogenic Mycobacterium reside inside vacuoles in their host macrophages. These vacuoles
fail to fuse with lysosomes yet interact with early endosomes. Glycoconjugates released …

The aggregation of the protein α‐synuclein (AS) is critical to the pathogenesis of Parkinson's
disease. Although generally described as an unstructured monomer, recent evidence …