NAIP–NLRC4-deficient mice are susceptible to shigellosis

PS Mitchell, JL Roncaioli, EA Turcotte, L Goers… - Elife, 2020 - elifesciences.org
Bacteria of the genus Shigella cause shigellosis, a severe gastrointestinal disease that is a
major cause of diarrhea-associated mortality in humans. Mice are highly resistant to Shigella …

Fungal gasdermin-like proteins are controlled by proteolytic cleavage

C Clavé, W Dyrka, EA Turcotte… - Proceedings of the …, 2022 - National Acad Sciences
Gasdermins are a family of pore-forming proteins controlling an inflammatory cell death reaction
in the mammalian immune system. The pore-forming ability of the gasdermin proteins is …

[HTML][HTML] Clinicians' perspectives on inertial measurement units in clinical practice

F Routhier, NC Duclos, É Lacroix, J Lettre, E Turcotte… - PLoS …, 2020 - journals.plos.org
Inertial measurement units (IMUs) have been increasingly popular in rehabilitation research.
However, despite their accessibility and potential advantages, their uptake and acceptance …

A hierarchy of cell death pathways confers layered resistance to shigellosis in mice

…, JP Babirye, RA Chavez, FL Liu, EA Turcotte… - Elife, 2023 - elifesciences.org
Bacteria of the genus Shigella cause shigellosis, a severe gastrointestinal disease driven
by bacterial colonization of colonic intestinal epithelial cells. Vertebrates have evolved …

[HTML][HTML] Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome

…, LK Castro, C Beierschmitt, C Yap, EA Turcotte… - PLoS …, 2023 - journals.plos.org
Hosts have evolved diverse strategies to respond to microbial infections, including the detection
of pathogen-encoded proteases by inflammasome-forming sensors such as NLRP1 and …

A human-specific motif facilitates CARD8 inflammasome activation after HIV-1 infection

J Kulsuptrakul, EA Turcotte, M Emerman, PS Mitchell - Elife, 2023 - elifesciences.org
Inflammasomes are cytosolic innate immune complexes that assemble upon detection of
diverse pathogen-associated cues and play a critical role in host defense and inflammatory …

Lipid bodies accumulation in Leishmania infantum‐infected C57BL/6 macrophages

NE Rodríguez, RD Lockard, EA Turcotte… - Parasite …, 2017 - Wiley Online Library
Lipid bodies ( LB s) are intracellular accumulations of neutral lipids surrounded by a single
membrane. These organelles are involved in the production of eicosanoids, which modulate …

[HTML][HTML] Epidemiological and experimental evidence for sex-dependent differences in the outcome of Leishmania infantum infection

…, ID Lima, UG Dixit, EA Turcotte… - The American journal …, 2018 - ncbi.nlm.nih.gov
Leishmania infantum causes visceral leishmaniasis (VL) in Brazil. We previously observed
that VL is more common in males than females living in endemic neighborhoods, despite …

The homespun paradox: market-oriented production of cloth in Eastern Canada in the nineteenth century

B Craig, J Rygiel, E Turcotte - Agricultural History, 2002 - JSTOR
Domestic manufacturing and outwork in the European countryside has erated a tremendous
amount of interest among historians. No suc nomenon has occurred among historians of …

[HTML][HTML] Experiences of social participation for Canadian wheelchair users with spinal cord injury during the first wave of the COVID-19 pandemic

…, A de Serres-Lafontaine, KL Best, C Rahn, E Turcotte… - Disabilities, 2022 - mdpi.com
The COVID-19 pandemic caused drastic life changes for people with spinal cord injury (SCI).
The objective of the study is to explore the social participation of Canadian wheelchair …