Lectin approaches for glycoproteomics in FDA-approved cancer biomarkers

…, BO Bekmanov, EM Khussainova… - Expert review of …, 2014 - Taylor & Francis
The nine FDA-approved protein biomarkers for the diagnosis and management of cancer
are approaching maturity, but their different glycosylation compositions relevant to early …

Ten millennia of hepatitis B virus evolution

…, M Rojo-Guerra, A Buzhilova, E Khussainova… - Science, 2021 - science.org
Hepatitis B virus (HBV) has been infecting humans for millennia and remains a global health
problem, but its past diversity and dispersal routes are largely unknown. We generated …

Stone Age Yersinia pestis genomes shed light on the early evolution, diversity, and ecology of plague

…, A Hübner, FM Key, E Khussainova… - Proceedings of the …, 2022 - National Acad Sciences
The bacterial pathogen Yersinia pestis gave rise to devastating outbreaks throughout human
history, and ancient DNA evidence has shown it afflicted human populations as far back as …

Ancient genomic time transect from the Central Asian Steppe unravels the history of the Scythians

GA Gnecchi-Ruscone, E Khussainova… - Science …, 2021 - science.org
The Scythians were a multitude of horse-warrior nomad cultures dwelling in the Eurasian
steppe during the first millennium BCE. Because of the lack of first-hand written records, little is …

The genetic history of admixture across inner Eurasia

…, A Immel, CC Wang, O Ixan, E Khussainova… - Nature ecology & …, 2019 - nature.com
The indigenous populations of inner Eurasia—a huge geographic region covering the
central Eurasian steppe and the northern Eurasian taiga and tundra—harbour tremendous …

[HTML][HTML] The determination of genetic markers of age-related cancer pathologies in populations from Kazakhstan

…, KB Djantaeva, OA Iksan, EM Khussainova - Frontiers in …, 2013 - frontiersin.org
Aging associates with a variety of pathological conditions such as cancer, cardiovascular,
neurodegenerative, autoimmune diseases, and metabolic disorders. The oncogenic …

[HTML][HTML] Genetic relationship among the Kazakh people based on Y-STR markers reveals evidence of genetic variation among tribes and zhuz

E Khussainova, I Kisselev, O Iksan, B Bekmanov… - Frontiers in …, 2022 - frontiersin.org
Ethnogenesis of Kazakhs took place in Central Asia, a region of high genetic and cultural
diversity. Even though archaeological and historical studies have shed some light on the …

Association of DCC, MLH1, GSTT1, GSTM1, and TP53 gene polymorphisms with colorectal cancer in Kazakhstan

L Djansugurova, G Zhunussova, E Khussainova… - Tumor Biology, 2015 - Springer
This study presents the first results of a molecular-genetic study of colorectal cancer (CRC)
in Kazakhstan. Blood samples were collected from patients diagnosed with rectal or colon …

[HTML][HTML] Individual Risk Assessment for Population Living on the Territories Long-Term Polluted by Organochlorine Pesticides

…, A Tolebaeva, Z Zhaniyazov, E Khussainova… - Toxics, 2023 - mdpi.com
The long-term storage of unutilized pesticides raised new problems of long-term environmental
contamination. The study presents the results of surveying 151 individuals in 7 villages …

[HTML][HTML] Comprehensive assessment of unutilized and obsolete pesticides impact on genetic status and health of population of Almaty region

…, M Delannoy, S Jurjanz, E Khussainova… - Ecotoxicology and …, 2020 - Elsevier
The group of persistent organic pollutants (POPs) are particularly dangerous for the environment
and by consequence for human health because of the risk to be transmitted in the food …