• The deployment of resistant crops often leads to the emergence of resistance‐breaking
pathogens that suppress the yield benefit provided by the resistance. Here, we theoretically …

RNA viruses generate defective viral genomes (DVGs) that can interfere with replication of
the parental wild-type virus. To examine their therapeutic potential, we created a DVG by …

The management of genes conferring resistance to plant–pathogens should make it possible
to control epidemics (epidemiological perspective) and preserve resistance durability (…

During replication, RNA viruses accumulate genome alterations, such as mutations and
deletions. The interactions between individual variants can determine the fitness of the virus …

Plant qualitative resistances to viruses are natural exhaustible resources that can be impaired
by the emergence of resistance-breaking (RB) virus variants. Mathematical modelling can …

Comparative metagenomics studies have highlighted differences in microbiome community
structure among human populations over diverse lifestyles and environments. With their …

By combining high-throughput sequencing (HTS) with experimental evolution, we can observe
the within-host dynamics of pathogen variants of biomedical or ecological interest. We …

The efficiency of plant major resistance genes is limited by the emergence and spread of
resistance‐breaking mutants. Modulation of the evolutionary forces acting on pathogen …

Drug–drug interactions (DDI) are a critical concern in healthcare due to their potential to cause
adverse effects and compromise patient safety. Supervised machine learning models for …

Infection of plants by viruses is a complex process involving several steps: inoculation into
plant cells, replication in inoculated cells and plant colonization. The success of the different …