Structure-activity relationships of mitochondria-targeted tetrapeptide pharmacological compounds
W Mitchell, JD Tamucci, EL Ng, S Liu, AV Birk… - Elife, 2022 - elifesciences.org
Mitochondria play a central role in metabolic homeostasis, and dysfunction of this organelle
underpins the etiology of many heritable and aging-related diseases. Tetrapeptides with …
underpins the etiology of many heritable and aging-related diseases. Tetrapeptides with …
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
We assembled an ancestrally diverse collection of genome-wide association studies (GWAS)
of type 2 diabetes (T2D) in 180,834 affected individuals and 1,159,055 controls (48.9% non…
of type 2 diabetes (T2D) in 180,834 affected individuals and 1,159,055 controls (48.9% non…
Author Spotlight: Decoding Mitochondrial Aging
EL Ng, AL Reed, CB O'Connell, NN Alder - JoVE (Journal of Visualized …, 2023 - jove.com
Mitochondria play many essential roles in the cell, including energy production, regulation
of Ca2+ homeostasis, lipid biosynthesis, and production of reactive oxygen species (ROS). …
of Ca2+ homeostasis, lipid biosynthesis, and production of reactive oxygen species (ROS). …
Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
We assembled an ancestrally diverse collection of genome-wide association studies of type
2 diabetes (T2D) in 180,834 cases and 1,159,055 controls (48.9% non-European descent). …
2 diabetes (T2D) in 180,834 cases and 1,159,055 controls (48.9% non-European descent). …
Structure-Activity Relationships in the Design of Mitochondria-Targeted Peptide Therapeutics
Mitochondria play a central role in metabolic homeostasis; hence, dysfunction of this
organelle underpins the etiology of many heritable and aging-related diseases. Mitochondria-…
organelle underpins the etiology of many heritable and aging-related diseases. Mitochondria-…
Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma
…, BL Levine, L Emery, L Litzky… - Blood, The Journal …, 2013 - ashpublications.org
… were elevated: troponin I was recorded at 54.4 ng/mL (normal range, 0.00 to 0.24 ng/mL)
and creatinine kinase MB at 65 ng/mL (normal range, 0 to 7 ng/mL). Within 30 minutes, he …
and creatinine kinase MB at 65 ng/mL (normal range, 0 to 7 ng/mL). Within 30 minutes, he …
Reference ranges for newer thyroid function tests in premature infants
LM Adams, JR Emery, SJ Clark, EI Carlton… - The Journal of …, 1995 - Elsevier
… Two reference ranges for free T 4 were determined, one for 25 to 30 weeks (6.4 to 42.5
pmol/L [0.5 to 3.3 ng/dl]) and one for 31 to 36 weeks (16.7 to 60.5 pmol/L [1.3 to 4.7 ng/dl]). The …
pmol/L [0.5 to 3.3 ng/dl]) and one for 31 to 36 weeks (16.7 to 60.5 pmol/L [1.3 to 4.7 ng/dl]). The …
[PDF][PDF] Associations of mitochondrial and nuclear mitochondrial variants and genes with seven metabolic traits
Mitochondria (MT), the major site of cellular energy production, are under dual genetic control
by 37 mitochondrial DNA (mtDNA) genes and numerous nuclear genes (MT-nDNA). In the …
by 37 mitochondrial DNA (mtDNA) genes and numerous nuclear genes (MT-nDNA). In the …
Direct space-charge calculation in elegant and its application to the ilc damping ring
…, M Borland, L Emery, Y Wang, KY Ng - 2007 IEEE Particle …, 2007 - ieeexplore.ieee.org
A direct space-charge force model has been implemented in the tracking code elegant [1].
The user can simulate transverse space-charge effects by inserting space- charge elements …
The user can simulate transverse space-charge effects by inserting space- charge elements …
Randomized controlled trial of rituximab and cost‐effectiveness analysis in treating fatigue and oral dryness in primary Sjögren's syndrome
Objective To investigate whether rituximab, an anti–B cell therapy, improves symptoms of
fatigue and oral dryness in patients with primary Sjögren's syndrome (SS). Methods We …
fatigue and oral dryness in patients with primary Sjögren's syndrome (SS). Methods We …