The development of an in vitro cell model that can be used to study severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) research is expected. Here we conducted infection …

It has been reported that many receptors and proteases are required for severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. Although angiotensin-converting …

Current in vitro 3D culture models lack a vascular system to transport oxygen and nutrients,
as well as cells, which is essential to maintain cellular viability and functions. Here, we …

Organs-on-chips are microfluidic devices typically fabricated from polydimethylsiloxane (PDMS).
Since PDMS has many attractive properties including high optical clarity and …

A liver-on-a-chip (liver-chip) is a microfluidic device carrying liver cells such as human
hepatocytes. It is used to reproduce a part of liver function. Many microfluidic devices are …

Genetic differences are a primary reason for differences in the susceptibility and severity of
COVID-19. As induced pluripotent stem (iPS) cells maintain the genetic information of the …

Polydimethylsiloxane (PDMS) is widely used to fabricate microfluidic organs-on-chips. Using
these devices (PDMS-based devices), the mechanical microenvironment of living tissues, …

… and diverse population (Sano et al., 2023). This chapter reviews the EMI situation in this …
Findings from this study suggest that students choose EMI courses to improve their English …

A fundamental limitation in the derivation of hematopoietic stem and progenitor cells is the
imprecise understanding of human developmental hematopoiesis. Herein we established a …

The (6–4) photoproduct is one of the major UV-induced lesions in DNA. We previously showed
that hydrolytic ring opening of the 5′ base and subsequent hydrolysis of the glycosidic …