Height is a highly heritable, classic polygenic trait with approximately 700 common associated
variants identified through genome-wide association studies so far. Here, we report 83 …

Birth weight (BW) has been shown to be influenced by both fetal and maternal factors and in
observational studies is reproducibly associated with future risk of adult metabolic diseases …

Birth weight variation is influenced by fetal and maternal genetic and non-genetic factors,
and has been reproducibly associated with future cardio-metabolic health outcomes. In …

Glycemic traits are used to diagnose and monitor type 2 diabetes and cardiometabolic health.
To date, most genetic studies of glycemic traits have focused on individuals of European …

Genetic studies promise to provide insight into the molecular mechanisms underlying type 2
diabetes (T2D). Variants associated with T2D are often located in tissue-specific enhancer …

The reanalysis of existing GWAS data represents a powerful and cost-effective opportunity
to gain insights into the genetics of complex diseases. By reanalyzing publicly available type …

Genome-wide association studies (GWAS) have found few common variants that influence
fasting measures of insulin sensitivity. We hypothesized that a GWAS of an integrated …

Aims We studied whether variants previously associated with congenital long QT syndrome (cLQTS)
have an effect on the QTc interval in a Danish population sample. Furthermore, we …

The role of rare variants in complex traits remains uncharted. Here, we conduct deep whole
genome sequencing of 1457 individuals from an isolated population, and test for rare variant …

The pig is a well-known animal model used to investigate genetic and mechanistic aspects of
human disease biology. They are particularly useful in the context of obesity and metabolic …