Abstract Characterization of the genetic landscape of Alzheimer’s disease (AD) and related
dementias (ADD) provides a unique opportunity for a better understanding of the associated …

Genetic discoveries of Alzheimer’s disease are the drivers of our understanding, and together
with polygenetic risk stratification can contribute towards planning of feasible and efficient …

Introduction Large variability among Alzheimer's disease (AD) cases might impact genetic
discoveries and complicate dissection of underlying biological pathways. Methods Genome …

Deciphering the genetic landscape of Alzheimer’s disease (AD) is essential to define the
pathophysiological pathways involved and to successfully translate genomics to potential …

Neuropsychiatric symptoms (NPS) have been recently addressed as risk factors of conversion
to Alzheimer’s disease (AD) and other dementia types in patients diagnosed with Mild …

… Emilio Alarcón-Martín …

Psychotic symptoms, defined as the occurrence of delusions or hallucinations, are frequent
in Alzheimer disease (AD with psychosis, AD + P). AD + P affects ~50% of individuals with AD…

Background: Clinical diagnosis of Alzheimer’s disease (AD) increasingly incorporates CSF
biomarkers. However, due to the intrinsic variability of the immunodetection techniques used …

Importance Amyloid positron emission tomography (PET) allows the direct assessment of
amyloid deposition, one of the main hallmarks of Alzheimer disease. However, this technique …

Alzheimer’s disease has a long asymptomatic phase that offers a substantial time window
for intervention. Using this window of opportunity will require early diagnostic and prognostic …