Definition of drug resistant epilepsy: consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies
To improve patient care and facilitate clinical research, the International League Against
Epilepsy (ILAE) appointed a Task Force to formulate a consensus definition of drug resistant …
Epilepsy (ILAE) appointed a Task Force to formulate a consensus definition of drug resistant …
ILAE official report: a practical clinical definition of epilepsy
…, BI Lee, GW Mathern, SL Moshé, E Perucca… - …, 2014 - Wiley Online Library
Epilepsy was defined conceptually in 2005 as a disorder of the brain characterized by an
enduring predisposition to generate epileptic seizures. This definition is usually practically …
enduring predisposition to generate epileptic seizures. This definition is usually practically …
Antiepileptic drugs—best practice guidelines for therapeutic drug monitoring: a position paper by the subcommission on therapeutic drug monitoring, ILAE …
…, SI Johannessen, IE Leppik, T Tomson, E Perucca - …, 2008 - Wiley Online Library
Although no randomized studies have demonstrated a positive impact of therapeutic drug
monitoring (TDM) on clinical outcome in epilepsy, evidence from nonrandomized studies and …
monitoring (TDM) on clinical outcome in epilepsy, evidence from nonrandomized studies and …
ILAE treatment guidelines: evidence‐based analysis of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes
…, C Guerreiro, R Kalviainen, R Mattson, E Perucca… - …, 2006 - Wiley Online Library
Purpose: To assess which antiepileptic medications (AEDs) have the best evidence for long‐term
efficacy or effectiveness as initial monotherapy for patients with newly diagnosed or …
efficacy or effectiveness as initial monotherapy for patients with newly diagnosed or …
Clinically relevant drug interactions with antiepileptic drugs
E Perucca - British journal of clinical pharmacology, 2006 - Wiley Online Library
Some patients with difficult‐to‐treat epilepsy benefit from combination therapy with two or
more antiepileptic drugs (AEDs). Additionally, virtually all epilepsy patients will receive, at …
more antiepileptic drugs (AEDs). Additionally, virtually all epilepsy patients will receive, at …
International League Against Epilepsy classification and definition of epilepsy syndromes with onset in childhood: Position paper by the ILAE Task Force on Nosology …
The 2017 International League Against Epilepsy classification has defined a three‐tier system
with epilepsy syndrome identification at the third level. Although a syndrome cannot be …
with epilepsy syndrome identification at the third level. Although a syndrome cannot be …
Epilepsy: new advances
Epilepsy affects 65 million people worldwide and entails a major burden in seizure-related
disability, mortality, comorbidities, stigma, and costs. In the past decade, important advances …
disability, mortality, comorbidities, stigma, and costs. In the past decade, important advances …
Pharmacological and therapeutic properties of valproate: a summary after 35 years of clinical experience
E Perucca - CNS drugs, 2002 - Springer
Thirty-five years since its introduction into clinical use, valproate (valproic acid) has become
the most widely prescribed antiepileptic drug (AED) worldwide. Its pharmacological effects …
the most widely prescribed antiepileptic drug (AED) worldwide. Its pharmacological effects …
ILAE classification of the epilepsies: Position paper of the ILAE Commission for Classification and Terminology
…, GW Mathern, SL Moshé, DR Nordli, E Perucca… - …, 2017 - Wiley Online Library
The International League Against Epilepsy ( ILAE ) Classification of the Epilepsies has been
updated to reflect our gain in understanding of the epilepsies and their underlying …
updated to reflect our gain in understanding of the epilepsies and their underlying …
International consensus classification of hippocampal sclerosis in temporal lobe epilepsy: a Task Force report from the ILAE Commission on Diagnostic Methods
Hippocampal sclerosis ( HS ) is the most frequent histopathology encountered in patients
with drug‐resistant temporal lobe epilepsy ( TLE ). Over the past decades, various attempts …
with drug‐resistant temporal lobe epilepsy ( TLE ). Over the past decades, various attempts …