Intelligence is highly heritable 1 and a major determinant of human health and well-being 2
. Recent genome-wide meta-analyses have identified 24 genomic loci linked to variation in …

General cognitive function is a prominent and relatively stable human trait that is associated
with many important life outcomes. We combine cognitive and genetic data from the …

The complex nature of human cognition has resulted in cognitive genomics lagging behind
many other fields in terms of gene discovery using genome-wide association study (GWAS) …

Background Accurate diagnosis and early detection of complex diseases, such as Parkinson's
disease, has the potential to be of great benefit for researchers and clinical practice. We …

Here, we present a large (n = 107,207) genome-wide association study (GWAS) of general
cognitive ability ("g"), further enhanced by combining results with a large-scale GWAS of …

Depression risk is exacerbated by genetic factors and stress exposure; however, the biological
mechanisms through which these factors interact to confer depression risk are poorly …

Susceptibility to schizophrenia is inversely correlated with general cognitive ability at both
the phenotypic and the genetic level. Paradoxically, a modest but consistent positive genetic …

Background The penetrance of leucine rich repeat kinase 2 (LRRK2) mutations is incomplete
and may be influenced by environmental and/or other genetic factors. Nonsteroidal anti‐…

Early life stress may precipitate psychopathology, at least in part, by influencing amygdala
function. Converging evidence across species suggests that links between childhood stress …

Background Preclinical models reveal that stress-induced amygdala activity and impairment
in fear extinction reflect reductions in anandamide driven by corticotropin-releasing factor …