[HTML][HTML] Epidemiology and molecular mechanisms tying obesity, diabetes, and the metabolic syndrome with cancer

EJ Gallagher, D LeRoith - Diabetes care, 2013 - ncbi.nlm.nih.gov
It is well recognized that the world is witnessing an epidemic of obesity and type 2 diabetes (T2D).
Numerous studies have shown that both obesity and T2D are associated with an …

Hyperinsulinaemia in cancer

EJ Gallagher, D LeRoith - Nature Reviews Cancer, 2020 - nature.com
Elevated circulating insulin levels are frequently observed in the setting of obesity and early
type 2 diabetes, as a result of insensitivity of metabolic tissues to the effects of insulin. Higher …

Obesity and diabetes: the increased risk of cancer and cancer-related mortality

EJ Gallagher, D LeRoith - Physiological reviews, 2015 - journals.physiology.org
Obesity and type 2 diabetes are becoming increasingly prevalent worldwide, and both are
associated with an increased incidence and mortality from many cancers. The metabolic …

[HTML][HTML] Early palliative care for patients with metastatic non–small-cell lung cancer

…, JA Greer, A Muzikansky, ER Gallagher… - … England Journal of …, 2010 - Mass Medical Soc
Background Patients with metastatic non–small-cell lung cancer have a substantial symptom
burden and may receive aggressive care at the end of life. We examined the effect of …

Association between early treatment with tocilizumab and mortality among critically ill patients with COVID-19

…, P Pattharanitima, EJ Gallagher… - JAMA internal …, 2021 - jamanetwork.com
Importance Therapies that improve survival in critically ill patients with coronavirus disease
2019 (COVID-19) are needed. Tocilizumab, a monoclonal antibody against the interleukin 6 …

[HTML][HTML] Effects of early integrated palliative care in patients with lung and GI cancer: a randomized clinical trial

…, EH Chittenden, SP Rinaldi, ER Gallagher… - Journal of Clinical …, 2017 - ncbi.nlm.nih.gov
Purpose We evaluated the impact of early integrated palliative care (PC) in patients with
newly diagnosed lung and GI cancer.

Longitudinal perceptions of prognosis and goals of therapy in patients with metastatic non–small-cell lung cancer: Results of a randomized study of early palliative …

…, JA Greer, S Admane, ER Gallagher… - Journal of clinical …, 2011 - ascopubs.org
Purpose Understanding of prognosis among terminally ill patients impacts medical decision
making. The aims of this study were to explore perceptions of prognosis and goals of …

Effect of early palliative care on chemotherapy use and end-of-life care in patients with metastatic non–small-cell lung cancer

…, IT Lennes, RS Heist, ER Gallagher… - Journal of Clinical …, 2012 - ascopubs.org
Purpose Prior research shows that introducing palliative care soon after diagnosis for patients
with metastatic non–small-cell lung cancer (NSCLC) is associated with improvements in …

Characteristics and outcomes of individuals with pre-existing kidney disease and COVID-19 admitted to intensive care units in the United States

…, GN Nadkarni, P Pattharanitima, EJ Gallagher… - American Journal of …, 2021 - Elsevier
Rationale & Objective Underlying kidney disease is an emerging risk factor for more severe
coronavirus disease 2019 (COVID-19) illness. We examined the clinical courses of critically …

Review of hemoglobin A1c in the management of diabetes

EJ Gallagher, D Le Roith, Z Bloomgarden - Journal of diabetes, 2009 - Wiley Online Library
Hemoglobin HbA 1c (A 1c ) has been used clinically since the 1980s as a test of glycemic
control in individuals with diabetes. The Diabetes Control and Complications Trial (DCCT) …