Glioblastoma multiforme (GBM), the most aggressive brain cancer, recurs because glioblastoma
stem cells (GSCs) are resistant to all standard therapies. We showed that GSCs, but not …

The neonatal mammalian heart is capable of regeneration for a brief window of time after
birth. However, this regenerative capacity is lost within the first week of life, which coincides …

Purpose: Natural killer (NK)-cell recognition and function against NK-resistant cancers remain
substantial barriers to the broad application of NK-cell immunotherapy. Potential solutions …

Natural killer (NK) cells are innate lymphocytes recognized for their important role against
tumor cells. NK cells expressing chimeric antigen receptors (CARs) have enhanced effector …

One hundred fifty‐three children 3 years of age or younger who had tracheotomies
performed during the past 15 years are reviewed. During this time, short‐term endotracheal …

Dedicated to the preservation and promotion of many of the nation’s most threatened and
endangered species, the WL Finley National Wildlife Refuge is highly invested in the …

Immune checkpoint therapy has resulted in remarkable improvements in the outcome for
certain cancers. To broaden the clinical impact of checkpoint targeting, we devised a strategy …

Trogocytosis is an active process that transfers surface material from targeted to effector
cells. Using multiple in vivo tumor models and clinical data, we report that chimeric antigen …

… I would like to dedicate this thesis to my parents, Paul and Salli Ensley, for their continuous
love and support. … Emily Louise Ensley was born in Houston, Texas, the daughter of Salli Jo …

Adoptive cell therapy with virus-specific T cells has been used successfully to treat life-threatening
viral infections, supporting application of this approach to coronavirus disease 2019 (…