User profiles for Emily M. Sontag
 | Emily SontagAssistant Professor, Marquette University Verified email at marquette.edu Cited by 1732 |
Sorting out the trash: the spatial nature of eukaryotic protein quality control
… Author links open overlay panel Emily M Sontag 1 , Willianne IM Vonk 1 , Judith Frydman …
Vendruscolo, M. Hayer-Hartl, FU Hartl, RM Vabulas … Ishii, M. Komatsu, NT Eissa …
Vendruscolo, M. Hayer-Hartl, FU Hartl, RM Vabulas … Ishii, M. Komatsu, NT Eissa …
Distinct proteostasis circuits cooperate in nuclear and cytoplasmic protein quality control
Protein misfolding is linked to a wide array of human disorders, including Alzheimer’s disease,
Parkinson’s disease and type II diabetes 1 , 2 . Protective cellular protein quality control (…
Parkinson’s disease and type II diabetes 1 , 2 . Protective cellular protein quality control (…
Nuclear and cytoplasmic spatial protein quality control is coordinated by nuclear–vacuolar junctions and perinuclear ESCRT
Effective protein quality control (PQC), essential for cellular health, relies on spatial
sequestration of misfolded proteins into defined inclusions. Here we reveal the coordination of …
sequestration of misfolded proteins into defined inclusions. Here we reveal the coordination of …
A transgenic minipig model of Huntington's Disease
…, P Musilova, R Vrtel, EM Sontag… - Journal of …, 2013 - content.iospress.com
Background: Some promising treatments for Huntington’s disease (HD) may require pre-clinical
testing in large animals. Minipig is a suitable species because of its large gyrencephalic …
testing in large animals. Minipig is a suitable species because of its large gyrencephalic …
[PDF][PDF] Multi-scale 3D cryo-correlative microscopy for vitrified cells
Three-dimensional (3D) visualization of vitrified cells can uncover structures of subcellular
complexes without chemical fixation or staining. Here, we present a pipeline integrating three …
complexes without chemical fixation or staining. Here, we present a pipeline integrating three …
Exogenous delivery of chaperonin subunit fragment ApiCCT1 modulates mutant Huntingtin cellular phenotypes
EM Sontag, LA Joachimiak, Z Tan… - Proceedings of the …, 2013 - National Acad Sciences
Aggregation of misfolded proteins is characteristic of a number of neurodegenerative
diseases, including Huntington disease (HD). The CCT/TRiC (chaperonin containing TCP-1/TCP-1 …
diseases, including Huntington disease (HD). The CCT/TRiC (chaperonin containing TCP-1/TCP-1 …
[HTML][HTML] Huntington's disease cerebrospinal fluid seeds aggregation of mutant huntingtin
Huntington’s disease (HD), a progressive neurodegenerative disease, is caused by an
expanded CAG triplet repeat producing a mutant huntingtin protein (mHTT) with a polyglutamine-…
expanded CAG triplet repeat producing a mutant huntingtin protein (mHTT) with a polyglutamine-…
An ESCRT-dependent pathway of Nuclear and Cytoplasmic Spatial PQC is coordinated at Nuclear Vacuolar Junctions
Spatial sequestration of misfolded proteins is an integral step in the process of cellular
Protein Quality Control (PQC). is essential for cellular health. One key PQC strategy relies on …
Protein Quality Control (PQC). is essential for cellular health. One key PQC strategy relies on …
[PDF][PDF] An ESCRT-dependent pathway coordinates Nuclear and Cytoplasmic Spatial Protein Quality Control at Nuclear Vacuolar Junctions
… & Hayer-Hartl, M. Molecular chaperones in protein folding and 511 … Crisp, M. et al.
Coupling of the nucleus and cytoplasm: role of the LINC complex. … Azkanaz, M. et al …
Coupling of the nucleus and cytoplasm: role of the LINC complex. … Azkanaz, M. et al …
[BOOK][B] Understanding Susan Sontag
C Rollyson - 2016 - books.google.com
… lives of Alice James and Emily Dickinson. In the economy of publishing, Sontag was the total
… , like other writers of her generation, Sontag enjoyed her share of State Department junkets …
… , like other writers of her generation, Sontag enjoyed her share of State Department junkets …