Detailed knowledge on how bacteria evade antibiotics and eventually develop resistance
could open avenues for novel therapeutics and diagnostics. It is thereby key to develop a …

Many bacterial species are represented by a pan-genome, whose genetic repertoire far
outstrips that of any single bacterial genome. Here we investigate how a bacterial pan-genome …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is continually evolving
resulting in variants with increased transmissibility, more severe disease, reduced effectiveness …

Background: The literature on neurological manifestations, cerebrospinal fluid analyses,
and autopsies in patients with COVID-19 continues to grow. The proposed mechanisms for …

Background Electronic health records (EHRs) with large sample sizes and rich information
offer great potential for dementia research, but current methods of phenotyping cognitive …

Herpesviruses have complex mechanisms enabling infection of the human CNS and evasion
of the immune system, allowing for indefinite latency in the host. Herpesvirus infections can …

Background: Data supporting dementia as a risk factor for coronavirus disease 2019 (COVID-19)
mortality relied on ICD-10 codes, yet nearly 40% of individuals with probable dementia …

Background Human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical
spastic paraparesis (HAM/TSP) is a chronic neurological condition characterized by …

Streptococcus pneumoniae is a prominent gram-positive commensal and opportunistic pathogen
which possesses a large pan-genome. Significant strain-to-strain variability in genomic …

Background Despite higher prevalence of cognitive disorders in people with human
immunodeficiency virus (PWH) and dementia being a risk factor for COVID-19 mortality, the …