Valproic acid increases formation of reactive oxygen species and induces apoptosis in postimplantation embryos: a role for oxidative stress in valproic acid-induced …

EWY Tung, LM Winn - Molecular pharmacology, 2011 - ASPET
Exposure to the anticonvulsant valproic acid (VPA) during the first trimester of pregnancy is
associated with an increased risk of congenital malformations including heart defects, …

Epigenetic modifications in valproic acid-induced teratogenesis

EWY Tung, LM Winn - Toxicology and applied pharmacology, 2010 - Elsevier
Exposure to the anticonvulsant drug valproic acid (VPA) in utero is associated with a 1–2%
increase in neural tube defects (NTDs), however the molecular mechanisms by which VPA …

Biological nitrogen fixation in maize: optimizing nitrogenase expression in a root-associated diazotroph

…, A Horton, O Smith, L Wu, E Tung… - Journal of …, 2020 - academic.oup.com
Plants depend upon beneficial interactions between roots and root-associated microorganisms
for growth promotion, disease suppression, and nutrient availability. This includes the …

[HTML][HTML] On the intrinsic sterility of 3D printing

RY Neches, KJ Flynn, L Zaman, E Tung, N Pudlo - PeerJ, 2016 - peerj.com
3D printers that build objects using extruded thermoplastic are quickly becoming commonplace
tools in laboratories. We demonstrate that, with appropriate handling, these devices are …

Benzo [a] pyrene increases DNA double strand break repair in vitro and in vivo: a possible mechanism for benzo [a] pyrene-induced toxicity

EWY Tung, NA Philbrook, CL Belanger, S Ansari… - … /Genetic Toxicology and …, 2014 - Elsevier
Benzo[a]pyrene (BaP) is a polycyclic aromatic hydrocarbon and carcinogen that is released
into the environment through natural and anthropogenic sources. BaP toxicity is dependent …

[HTML][HTML] Firemaster® 550 and its components isopropylated triphenyl phosphate and triphenyl phosphate enhance adipogenesis and transcriptional activity of …

EWY Tung, S Ahmed, V Peshdary, E Atlas - PloS one, 2017 - journals.plos.org
Firemaster ® 550 (FM550) is a chemical mixture currently used as an additive flame retardant
in commercial products, and is comprised of 2-ethylhexyl-2,3,4,5-tertrabromobenzoate (…

[HTML][HTML] Induction of adipocyte differentiation by polybrominated diphenyl ethers (PBDEs) in 3T3-L1 cells

EWY Tung, A Boudreau, MG Wade, E Atlas - PloS one, 2014 - journals.plos.org
Polybrominated diphenyl ethers (PBDEs) are a class of brominated flame retardants that
were extensively used in commercial products. PBDEs are ubiquitous environmental …

Gestational and early postnatal exposure to an environmentally relevant mixture of brominated flame retardants: General toxicity and skeletal variations

EWY Tung, H Yan, PLC Lefèvre… - … Research Part B …, 2016 - Wiley Online Library
Brominated flame retardants (BFRs) are stable environmental contaminants known to exert
endocrine‐disrupting effects. Developmental exposure to polybrominated diphenyl ethers (…

Adipogenic effects and gene expression profiling of Firemaster® 550 components in human primary preadipocytes

EWY Tung, V Peshdary, R Gagné… - Environmental …, 2017 - ehp.niehs.nih.gov
Background: Exposure to flame retardants has been associated with negative health
outcomes including metabolic effects. As polybrominated diphenyl ether flame retardants were …

DNA double-strand breaks and DNA recombination in benzene Metabolite–Induced genotoxicity

EWY Tung, NA Philbrook, KDD MacDonald… - Toxicological …, 2012 - academic.oup.com
In utero exposure to environmental carcinogens, including the ubiquitous pollutant benzene,
may cause DNA damage in the fetus, leading to an increased risk for the development of …