Hematopoietic stem cell transplantation (HSCT) is an effective treatment option for several
malignant and non-malignant hematological diseases. The clinical outcome of this procedure …

Background Since allogeneic stem-cell transplantation can induce curative graft-versus-leukemia
reactions in patients with hematologic cancers, we sought to induce analogous graft-…

As the thymus represents the primary site of T-cell development, optimal thymic function is
of paramount importance for the successful reconstitution of the adaptive immunity after …

Cord blood (CB) is used increasingly as a source of hematopoietic stem cells because of a
lower risk of acute and chronic graft-versus-host disease (GVHD). However, there is some …

We previously showed that a peptide (PR1) derived from the primary granule enzyme
proteinase 3 induced peptide specific cytotoxic T lymphocytes (CTL) in a normal HLA-A2.1 + …

Long-term T-cell reconstitution after hematopoietic stem cell transplantation (HSCT) is
dependent on patient thymic function and affected by graft-versus-host disease (GVHD). To …

Th17 cells have never been explored in human graft-versus-host disease (GVHD). We studied
the correlation between the presence of Th17 cells with histologic and clinical parameters…

Objective To analyze hematopoietic and immune reconstitution after autologous hematopoietic
stem cell transplantation (HSCT) in 7 patients with systemic sclerosis (SSc). Methods …

Thirty-eight patients with hematological malignancies, received T cell-depleted marrow
transplants (BMT) and cyclosporine to prevent acute graft-versus-host disease (aGVHD), …

PURPOSE: A 50-year-old man developed progressive pulmonary metastasis resistant to
interferon alfa-2b treatment 7 months after he underwent left nephrectomy for stage III renal cell …