Structural basis of transcription-translation coupling

C Wang, V Molodtsov, E Firlar, JT Kaelber, G Blaha… - Science, 2020 - science.org
In bacteria, transcription and translation are coupled processes in which the movement of
RNA polymerase (RNAP)–synthesizing messenger RNA (mRNA) is coordinated with the …

Structural basis of Rho-dependent transcription termination

V Molodtsov, C Wang, E Firlar, JT Kaelber, RH Ebright - Nature, 2023 - nature.com
Rho is a ring-shaped hexameric ATP-dependent molecular motor. Together with the transcription
elongation factor NusG, Rho mediates factor-dependent transcription termination and …

[HTML][HTML] Sustained micellar delivery via inducible transitions in nanostructure morphology

…, S Allen, HK Kwon, S Bobbala, E Firlar… - Nature …, 2018 - nature.com
Nanocarrier administration has primarily been restricted to intermittent bolus injections with
limited available options for sustained delivery in vivo. Here, we demonstrate that cylinder-to-…

[HTML][HTML] Correlative Electron and Fluorescence Microscopy of Magnetotactic Bacteria in Liquid: Toward In Vivo Imaging

TJ Woehl, S Kashyap, E Firlar, T Perez-Gonzalez… - Scientific Reports, 2014 - nature.com
Magnetotactic bacteria biomineralize ordered chains of uniform, membrane-bound
magnetite or greigite nanocrystals that exhibit nearly perfect crystal structures and species-specific …

TEM studies on antibacterial mechanisms of black phosphorous nanosheets

AH Phakatkar, E Firlar, L Alzate, B Song… - International Journal …, 2020 - Taylor & Francis
Purpose Recently, two-dimensional (2D) nanomaterials are gaining tremendous attention
as novel antibacterial platforms to combat against continuously evolving antimicrobial …

In Situ Liquid‐Cell TEM Observation of Multiphase Classical and Nonclassical Nucleation of Calcium Oxalate

DJ Banner, E Firlar, P Rehak… - Advanced Functional …, 2021 - Wiley Online Library
Calcium oxalate (CaOx) is the major phase in kidney stones and the primary calcium storage
medium in plants. CaOx can form crystals with different lattice types, water contents, and …

Investigation of the magnetosome biomineralization in magnetotactic bacteria using graphene liquid cell–transmission electron microscopy

E Firlar, M Ouy, A Bogdanowicz, L Covnot, B Song… - Nanoscale, 2019 - pubs.rsc.org
Understanding the biomineralization pathways in living biological species is a grand challenge
owing to the difficulties in monitoring the mineralization process at sub-nanometer scales…

Combination targeting of 'platelets+ fibrin'enhances clot anchorage efficiency of nanoparticles for vascular drug delivery

M Sun, K Miyazawa, T Pendekanti, A Razmi, E Firlar… - Nanoscale, 2020 - pubs.rsc.org
Occlusive thrombosis is a central pathological event in heart attack, stroke, thromboembolism,
etc. Therefore, pharmacological thrombolysis or anticoagulation is used for treating these …

On the structure and chemistry of iron oxide cores in human heart and human spleen ferritins using graphene liquid cell electron microscopy

S Narayanan, E Firlar, MG Rasul, T Foroozan… - Nanoscale, 2019 - pubs.rsc.org
Ferritin is a protein that regulates the iron ions in humans by storing them in the form of iron
oxides. Despite extensive efforts to understand the ferritin iron oxide structures, it is still not …

[HTML][HTML] Direct Visualization of the Hydration Layer on Alumina Nanoparticles with the Fluid Cell STEM in situ

E Firlar, S Çınar, S Kashyap, M Akinc, T Prozorov - Scientific Reports, 2015 - nature.com
Rheological behavior of aqueous suspensions containing nanometer-sized powders is of
relevance to many branches of industry. Unusually high viscosities observed for suspensions …