User profiles for Enda M Byrne
Enda ByrneUniversity of Queensland, Child Health Research Centre, Brisbane, Australia Verified email at uq.edu.au Cited by 21562 |
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Major depressive disorder (MDD) is a common illness accompanied by considerable
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions
Major depression is a debilitating psychiatric illness that is typically associated with low
mood and anhedonia. Depression has a heritable component that has remained difficult to …
mood and anhedonia. Depression has a heritable component that has remained difficult to …
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
Schizophrenia is a debilitating psychiatric condition often associated with poor quality of life
and decreased life expectancy. Lack of progress in improving treatment outcomes has been …
and decreased life expectancy. Lack of progress in improving treatment outcomes has been …
Genome-wide association study identifies 30 loci associated with bipolar disorder
…, JMW Pavlides, M Trzaskowski, EM Byrne… - Nature …, 2019 - nature.com
Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide
association study (GWAS) including 20,352 cases and 31,358 controls of European descent, …
association study (GWAS) including 20,352 cases and 31,358 controls of European descent, …
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies
To identify loci for age at menarche, we performed a meta-analysis of 32 genome-wide
association studies in 87,802 women of European descent, with replication in up to 14,731 …
association studies in 87,802 women of European descent, with replication in up to 14,731 …
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche
Age at menarche is a marker of timing of puberty in females. It varies widely between
individuals, is a heritable trait and is associated with risks for obesity, type 2 diabetes, …
individuals, is a heritable trait and is associated with risks for obesity, type 2 diabetes, …
Meta-analysis of genome-wide association studies of anxiety disorders
Anxiety disorders (ADs), namely generalized AD, panic disorder and phobias, are common,
etiologically complex conditions with a partially genetic basis. Despite differing on diagnostic …
etiologically complex conditions with a partially genetic basis. Despite differing on diagnostic …
[HTML][HTML] Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms
…, JW Harrison, A Dawes, EM Byrne… - Nature …, 2019 - nature.com
Being a morning person is a behavioural indicator of a person’s underlying circadian rhythm.
Using genome-wide data from 697,828 UK Biobank and 23andMe participants we …
Using genome-wide data from 697,828 UK Biobank and 23andMe participants we …
Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression
The hypothesis that the S allele of the 5-HTTLPR serotonin transporter promoter region is
associated with increased risk of depression, but only in individuals exposed to stressful …
associated with increased risk of depression, but only in individuals exposed to stressful …
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22
genome-wide association studies (GWAS) in 38,968 women of European descent, with …
genome-wide association studies (GWAS) in 38,968 women of European descent, with …