Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation

…, T Goldfarb, T Gupta, D Haft, E Hatcher… - Nucleic acids …, 2016 - academic.oup.com
The RefSeq project at the National Center for Biotechnology Information (NCBI) maintains
and curates a publicly available database of annotated genomic, transcript, and protein …

Virus Variation Resource–improved response to emergent viral outbreaks

EL Hatcher, SA Zhdanov, Y Bao, O Blinkova… - Nucleic acids …, 2017 - academic.oup.com
The Virus Variation Resource is a value-added viral sequence data resource hosted by the
National Center for Biotechnology Information. The resource is located at http://www.ncbi.nlm.…

Orthopoxvirus genome evolution: the role of gene loss

RC Hendrickson, C Wang, EL Hatcher, EJ Lefkowitz - Viruses, 2010 - mdpi.com
Poxviruses are highly successful pathogens, known to infect a variety of hosts. The family
Poxviridae includes Variola virus, the causative agent of smallpox, which has been eradicated …

[HTML][HTML] Database resources of the National Center for Biotechnology Information in 2023

…, M Feldgarden, AM Fine, K Funk, E Hatcher… - Nucleic acids …, 2023 - ncbi.nlm.nih.gov
The National Center for Biotechnology Information (NCBI) provides online information resources
for biology, including the GenBank® nucleic acid sequence database and the PubMed…

[HTML][HTML] FDA-ARGOS is a database with public quality-controlled reference genomes for diagnostic use and regulatory science

…, L Sadzewicz, S Nadendla, W Klimke, E Hatcher… - Nature …, 2019 - nature.com
FDA proactively invests in tools to support innovation of emerging technologies, such as
infectious disease next generation sequencing (ID-NGS). Here, we introduce FDA-ARGOS …

[HTML][HTML] VADR: validation and annotation of virus sequence submissions to GenBank

AA Schäffer, EL Hatcher, L Yankie, L Shonkwiler… - BMC …, 2020 - Springer
Background GenBank contains over 3 million viral sequences. The National Center for
Biotechnology Information (NCBI) previously made available a tool for validating and annotating …

[HTML][HTML] Proposal for human respiratory syncytial virus nomenclature below the species level

…, M Galiano, BS Graham, EL Hatcher… - Emerging infectious …, 2021 - ncbi.nlm.nih.gov
Human respiratory syncytial virus (HRSV) is the leading viral cause of serious pediatric
respiratory disease, and lifelong reinfections are common. Its 2 major subgroups, A and B, exhibit …

[HTML][HTML] The Phylogeny and Pathogenesis of Sacbrood Virus (SBV) Infection in European Honey Bees, Apis mellifera

…, O Banmeke, JR Brister, EL Hatcher… - Viruses, 2019 - mdpi.com
RNA viruses that contain single-stranded RNA genomes of positive sense make up the largest
group of pathogens infecting honey bees. Sacbrood virus (SBV) is one of the most widely …

[HTML][HTML] Genome variability and gene content in chordopoxviruses: dependence on microsatellites

EL Hatcher, C Wang, EJ Lefkowitz - Viruses, 2015 - mdpi.com
To investigate gene loss in poxviruses belonging to the Chordopoxvirinae subfamily, we
assessed the gene content of representative members of the subfamily, and determined …

Identification of nucleotide-level changes impacting gene content and genome evolution in orthopoxviruses

EL Hatcher, RC Hendrickson, EJ Lefkowitz - Journal of Virology, 2014 - Am Soc Microbiol
Poxviruses are composed of large double-stranded DNA (dsDNA) genomes coding for several
hundred genes whose variation has supported virus adaptation to a wide variety of hosts …