User profiles for Enzo Mameli

Enzo Mameli

Postdoctoral Research Fellow, Harvard Medical School
Verified email at hms.harvard.edu
Cited by 186

Sexual transfer of the steroid hormone 20E induces the postmating switch in Anopheles gambiae

…, EG Kakani, SN Mitchell, E Mameli… - Proceedings of the …, 2014 - National Acad Sciences
Female insects generally mate multiple times during their lives. A notable exception is the
female malaria mosquito Anopheles gambiae, which after sex loses her susceptibility to further …

[HTML][HTML] Tick hemocytes have a pleiotropic role in microbial infection and arthropod fitness

…, AJ O'Neal, CR Ferraz, M Butnaru, E Mameli… - Nature …, 2024 - nature.com
Uncovering the complexity of systems in non-model organisms is critical for understanding
arthropod immunology. Prior efforts have mostly focused on Dipteran insects, which only …

[HTML][HTML] Optimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes

X Feng, V López Del Amo, E Mameli, M Lee… - Nature …, 2021 - nature.com
Culex mosquitoes are a global vector for multiple human and animal diseases, including West
Nile virus, lymphatic filariasis, and avian malaria, posing a constant threat to public health, …

[HTML][HTML] A male steroid controls female sexual behaviour in the malaria mosquito

D Peng, EG Kakani, E Mameli, C Vidoudez, SN Mitchell… - Nature, 2022 - nature.com
Insects, unlike vertebrates, are widely believed to lack male-biased sex steroid hormones 1
. In the malaria mosquito Anopheles gambiae, the ecdysteroid 20-hydroxyecdysone (20E) …

[HTML][HTML] Dengue Virus-2 Infection Affects Fecundity and Elicits Specific Transcriptional Changes in the Ovaries of Aedes aegypti Mosquitoes

F Feitosa-Suntheimer, Z Zhu, E Mameli… - Frontiers in …, 2022 - frontiersin.org
Dengue fever (DF), caused by the dengue virus (DENV), is the most burdensome arboviral
disease in the world, with an estimated 400 million infections each year. The Aedes aegypti …

[HTML][HTML] Bioinformatic and cell-based tools for pooled CRISPR knockout screening in mosquitos

R Viswanatha, E Mameli, J Rodiger, P Merckaert… - Nature …, 2021 - nature.com
Mosquito-borne diseases present a worldwide public health burden. Current efforts to understand
and counteract them have been aided by the use of cultured mosquito cells. Moreover, …

[HTML][HTML] A transgenic tool to assess Anopheles mating competitiveness in the field

AL Smidler, SN Scott, E Mameli, WR Shaw… - Parasites & vectors, 2018 - Springer
Background Malaria parasites, transmitted by the bite of an anopheline mosquito, pose an
immense public health burden on many tropical and subtropical regions. The most important …

[HTML][HTML] Mating-regulated atrial proteases control reinsemination rates in Anopheles gambiae females

P Bascuñán, P Gabrieli, E Mameli, F Catteruccia - Scientific Reports, 2020 - nature.com
Anopheles gambiae mosquitoes are the most important vectors of human malaria. The
reproductive success of these mosquitoes relies on a single copulation event after which the …

Optimized CRISPR tools and site-directed transgenesis in Culex quinquefasciatus mosquitoes for gene drive development

X Feng, VL Del Amo, E Mameli, M Lee, AL Bishop… - bioRxiv, 2021 - biorxiv.org
Culex mosquitoes are a global vector for multiple human and animal diseases, including West
Nile virus, lymphatic filariasis, and avian malaria, posing a constant threat to public health, …

Author Correction: Bioinformatic and cell-based tools for pooled CRISPR knockout screening in mosquitos

R Viswanatha, E Mameli, J Rodiger… - Nature …, 2022 - nature.com
The original version of this Article contained an error in Fig. 5, in which the A. coluzzii ortholog
of PTP-ER AGAP007118 was incorrectly listed as AGAP028616. In addition, the sentence “…