User profiles for Eralda Salataj
Eralda SalatajCornell University Verified email at med.cornell.edu Cited by 486 |
G-CSF in tumors: Aggressiveness, tumor microenvironment and immune cell regulation
Granulocyte colony-stimulating factor (G-CSF) is a cytokine most well-known for maturation
and mobilization of bone marrow neutrophils. Although it is used therapeutically to treat …
and mobilization of bone marrow neutrophils. Although it is used therapeutically to treat …
[PDF][PDF] Precise gene editing preserves hematopoietic stem cell function following transient p53-mediated DNA damage response
…, A Calabria, V Vavassori, P Gasparini, E Salataj… - Cell stem cell, 2019 - cell.com
Precise gene editing in hematopoietic stem and progenitor cells (HSPCs) holds promise for
treating genetic diseases. However, responses triggered by programmable nucleases in …
treating genetic diseases. However, responses triggered by programmable nucleases in …
[HTML][HTML] Association of nutraceutical supplements with longer telomere length
Telomeres are nucleotide tandem repeats located at the tip of eukaryotic chromosomes that
maintain genomic integrity. The gradual shortening of telomeres leads to cellular …
maintain genomic integrity. The gradual shortening of telomeres leads to cellular …
[HTML][HTML] Deciphering the complexity of 3D chromatin organization driving lymphopoiesis and lymphoid malignancies
Proper lymphopoiesis and immune responses depend on the spatiotemporal control of multiple
processes, including gene expression, DNA recombination and cell fate decisions. High-…
processes, including gene expression, DNA recombination and cell fate decisions. High-…
3D Enhancer–promoter networks provide predictive features for gene expression and coregulation in early embryonic lineages
D Murphy, E Salataj, DC Di Giammartino… - Nature Structural & …, 2024 - nature.com
Mammalian embryogenesis commences with two pivotal and binary cell fate decisions that
give rise to three essential lineages: the trophectoderm, the epiblast and the primitive …
give rise to three essential lineages: the trophectoderm, the epiblast and the primitive …
Alterations of deadenylase expression in acute leukemias: evidence for poly (a)-specific ribonuclease as a potential biomarker
Background/Aims: The degradation of mRNA is a key process in the control of gene expression
correlated to anomalous cell proliferation. The rate-limiting step of mRNA degradation is …
correlated to anomalous cell proliferation. The rate-limiting step of mRNA degradation is …
Screening of ETO2-GLIS2–induced Super Enhancers identifies targetable cooperative dependencies in acute megakaryoblastic leukemia
Super Enhancers (SEs) are clusters of regulatory elements associated with cell identity and
disease. However, whether these elements are induced by oncogenes and can regulate …
disease. However, whether these elements are induced by oncogenes and can regulate …
[HTML][HTML] Single-cell detection of primary transcripts, their genomic loci and nuclear factors by 3D immuno-RNA/DNA FISH in T cells
E Salataj, CG Spilianakis, J Chaumeil - Frontiers in Immunology, 2023 - frontiersin.org
Over the past decades, it has become increasingly clear that higher order chromatin folding
and organization within the nucleus is involved in the regulation of genome activity and …
and organization within the nucleus is involved in the regulation of genome activity and …
[HTML][HTML] Single-cell analysis of bidirectional reprogramming between early embryonic states reveals mechanisms of differential lineage plasticities
Two distinct fates, pluripotent epiblast (EPI) and primitive (extra-embryonic) endoderm (PrE),
arise from common progenitor cells, the inner cell mass (ICM), in mammalian embryos. To …
arise from common progenitor cells, the inner cell mass (ICM), in mammalian embryos. To …
[HTML][HTML] Developmental conservation of microRNA gene localization at the nuclear periphery
E Salataj, C Stathopoulou, RA Hafţórsson… - PloS One, 2019 - journals.plos.org
microRNAs are of vital importance for the regulation of the adaptive and innate immune
responses, modulating gene expression at the post transcriptional level. Although there is …
responses, modulating gene expression at the post transcriptional level. Although there is …