User profiles for Eric A. Gaucher

Eric Gaucher

Professor & Director of the School of Biology, Georgia State University
Verified email at gsu.edu
Cited by 5891

Palaeotemperature trend for Precambrian life inferred from resurrected proteins

EA Gaucher, S Govindarajan, OK Ganesh - Nature, 2008 - nature.com
Biosignatures and structures in the geological record indicate that microbial life has inhabited
Earth for the past 3.5 billion years or so 1 , 2 . Research in the physical sciences has been …

Thermoddem: A geochemical database focused on low temperature water/rock interactions and waste materials

…, M Azaroual, N Jacquemet, A Fabbri, EC Gaucher - Applied …, 2012 - Elsevier
The development of Thermoddem, a thermodynamic database devoted to geochemical
modelling for environmental studies in general and, more specifically, to chemical systems …

Resurrecting ancestral alcohol dehydrogenases from yeast

JM Thomson, EA Gaucher, MF Burgan, DW De Kee… - Nature …, 2005 - nature.com
Modern yeast living in fleshy fruits rapidly convert sugars into bulk ethanol through pyruvate.
Pyruvate loses carbon dioxide to produce acetaldehyde, which is reduced by alcohol …

Evolutionary history and metabolic insights of ancient mammalian uricases

…, EA Ortlund, RJ Johnson, EA Gaucher - Proceedings of the …, 2014 - National Acad Sciences
Uricase is an enzyme involved in purine catabolism and is found in all three domains of life.
Curiously, uricase is not functional in some organisms despite its role in converting highly …

Cement/clay interactions–a review: experiments, natural analogues, and modeling

EC Gaucher, P Blanc - Waste Management, 2006 - Elsevier
The concept of storing radioactive waste in geological formations calls for large quantities of
concrete that will be in contact with the clay material of the engineered barriers as well as …

Inferring the palaeoenvironment of ancient bacteria on the basis of resurrected proteins

EA Gaucher, JM Thomson, MF Burgan, SA Benner - Nature, 2003 - nature.com
Features of the physical environment surrounding an ancestral organism can be inferred by
reconstructing sequences 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 of ancient proteins made by those …

Hyperstability and substrate promiscuity in laboratory resurrections of Precambrian β-lactamases

…, DF Mejia-Carmona, EA Gaucher… - Journal of the …, 2013 - ACS Publications
We report a sequence reconstruction analysis targeting several Precambrian nodes in the
evolution of class-A β-lactamases and the preparation and experimental characterization of …

Single-molecule paleoenzymology probes the chemistry of resurrected enzymes

…, A Holmgren, JM Sanchez-Ruiz, EA Gaucher… - Nature structural & …, 2011 - nature.com
It is possible to travel back in time at the molecular level by reconstructing proteins from
extinct organisms. Here we report the reconstruction, based on sequence predicted by …

A robust model for pore-water chemistry of clayrock

EC Gaucher, C Tournassat, FJ Pearson, P Blanc… - … et Cosmochimica Acta, 2009 - Elsevier
The chemistry of pore water is an important property of clayrocks being considered as host
rocks for long-term storage of radioactive waste. It may be difficult, if not impossible, to obtain …

Development of an attrition-leaching hybrid process for direct aqueous mineral carbonation

…, F Guyot, F Bodénan, C Petiot, ÉC Gaucher - Chemical Engineering …, 2015 - Elsevier
Mineral carbonation is the single most eligible companion solution to geosequestration for
mitigation of anthropic CO 2 emissions on a large scale. Amongst its possible pathways, …