Excitation–contraction coupling, the process that regulates contractions by skeletal muscles,
transduces changes in membrane voltage by activating release of Ca 2+ from internal …

Rapid escape swims in fish are initiated by the Mauthner cells, giant reticulospinal neurons
with unique specializations for swift responses. The Mauthner cells directly activate …

Many genetic manipulations are limited by difficulty in obtaining adequate levels of protein
expression. Bioinformatic and experimental studies have identified nucleotide sequence …

Atlases provide a framework for spatially mapping information from diverse sources into a
common reference space. Specifically, brain atlases allow annotation of gene expression, cell …

A new and exciting phase of muscle disease research has recently been entered. The application
of next generation sequencing technology has spurred an unprecedented era of gene …

Skeletal muscle contractions are initiated by an increase in Ca 2+ released during excitation–contraction
(EC) coupling, and defects in EC coupling are associated with human …

Background Animals use sensory cues to efficiently locate resources, but when sensory
information is insufficient, they may rely on internally coded search strategies. Despite the …

Large-scale genomic studies have recently identified genetic variants causative for major
neurodevelopmental disorders, such as intellectual disability and autism. However, …

Asymmetries in motor behavior, such as human hand preference, are observed throughout
bilateria. However, neural substrates and developmental signaling pathways that impose …

Vascular endothelial growth factor (VEGF) is a major mediator of pathologic angiogenesis,
a process necessary for the formation of new blood vessels to support tumor growth. …