The extent to which microorganisms impair wound healing is an ongoing controversy in the
management of chronic wounds. Because the high diversity and extreme variability of the …

Background Chronic wounds affect millions of people and cost billions of dollars in the United
States each year. These wounds harbor polymicrobial biofilm communities, which can be …

Herpes simplex virus type-1 (HSV-1) is one of the most widespread pathogens among
humans. Although the structure of HSV-1 has been extensively investigated, the precise …

A new method is presented for performing the Abel inversion by fitting the line-of-sight projection
of a predefined intensity distribution (FLiPPID) to the recorded 2D projections. The aim …

Localization microscopy software generally contains three elements: a localization algorithm
to determine fluorophore positions on a specimen, a quality control method to exclude …

Mitochondrial dysfunction has long been implicated in the neurodegenerative disorder
Parkinson's disease (PD); however, it is unclear how mitochondrial impairment and α-synuclein …

The three-dimensional imaging of mesoscopic samples with Optical Projection Tomography
(OPT) has become a powerful tool for biomedical phenotyping studies. OPT uses visible …

Background This paper analyses the resolution achieved in localisation microscopy
experiments. The resolution is an essential metric for the correct interpretation of super-resolution …

Fluorescence anisotropy measurements of reagents compartmentalized into individual
nanoliter droplets are shown to yield high-resolution binding curves from which precise …

The germination of Bacillus spores is triggered by certain amino acids and sugar molecules
which permeate the outermost layers of the spore to interact with receptor complexes that …