Recently, several new ophthalmic NSAID products have been introduced for commercial
use in the United States. The purpose of this review is to briefly overview the ophthalmic …

PURPOSE: To compare the incidence of visually significant pseudophakic macular edema
after uneventful phacoemulsification in patients treated postoperatively with topical …

With the rapid growth of synthetic messenger RNA (mRNA)-based therapeutics and
vaccines, the development of analytical tools for characterization of long, complex RNAs has …

We describe a patient with systemic graft-versus-host disease who developed a nonhealing
epithelial defect after cataract surgery that healed on cessation of a topical nonsteroidal …

While splicing has been shown to enhance nuclear export, it has remained unclear whether
mRNAs generated from intronless genes use specific machinery to promote their export. …

The N7-methyl guanosine cap structure is an essential 5′ end modification of eukaryotic
mRNA. It plays a critical role in many aspects of the life cycle of mRNA, including nuclear export…

The phosphorylated RNA polymerase II CTD interacting factor 1 (PCIF1) is a methyltransferase
that adds a methyl group to the N6-position of 2′O-methyladenosine (A m ), generating …

The mammalian mRNA nuclear export process is thought to terminate at the cytoplasmic face
of the nuclear pore complex through ribonucleoprotein remodeling. We conduct a stringent …

Combinations of ribonucleases (RNases) are commonly used to digest RNA into oligoribonucleotide
fragments prior to liquid chromatography-mass spectrometry (LC-MS) analysis. The …

Quality control of mRNA represents an important regulatory mechanism for gene expression
in eukaryotes. One component of this quality control is the nuclear retention and decay of …