In mammalian cells, DNA methylation on the fifth position of cytosine (5mC) plays an important
role as an epigenetic mark. However, DNA methylation was considered to be absent in C. …

N 6 -Methyladenosine (m 6 A) is one of the most abundant modifications of the epitranscriptome
and is found in cellular RNAs across all kingdoms of life. Advances in detection and …

Animals sense and adapt to decreased oxygen availability, but whether and how hypoxia
exposure in ancestors can elicit phenotypic consequences in normoxia-reared descendants …

During stress, global translation is reduced, but specific transcripts are actively translated.
How stress-responsive mRNAs are selectively translated is unknown. We show that METL-5 …

Background The evolution of multicellularity is a critical event that remains incompletely
understood. We use the social amoeba, Dictyostelium discoideum, one of the rare organisms …

DNA N 6 -adenine methylation (N 6 -methyladenine; 6mA) in prokaryotes functions primarily
in the host defence system. The prevalence and significance of this modification in …

mRNAs are regulated by nucleotide modifications that influence their cellular fate. Two of
the most abundant modified nucleotides are N 6 -methyladenosine (m 6 A), found within …

N 6 -methyl-2′-deoxyadenosine (6mA or m 6 dA) has been reported in the DNA of prokaryotes
and eukaryotes ranging from unicellular protozoa and algae to multicellular plants and …

Chromatin, consisting of deoxyribonucleic acid (DNA) wrapped around histone proteins,
facilitates DNA compaction and allows identical DNA codes to confer many different cellular …

Highlights • Examples of transgenerational epigenetic inheritance of brain related phenotypes.
• Overview of putative molecular carriers of non-genetic information are described. • …