User profiles for Eric S. Loker
 | Eric S. LokerProfessor of Biology, University of New Mexico Verified email at unm.edu Cited by 12237 |
Invertebrate immune systems–not homogeneous, not simple, not well understood
The approximate 30 extant invertebrate phyla have diversified along separate evolutionary
trajectories for hundreds of millions of years. Although recent work understandably has …
trajectories for hundreds of millions of years. Although recent work understandably has …
[HTML][HTML] Reduced Susceptibility to Praziquantel among Naturally Occurring Kenyan Isolates of Schistosoma mansoni
Background The near exclusive use of praziquantel (PZQ) for treatment of human schistosomiasis
has raised concerns about the possible emergence of drug-resistant schistosomes. …
has raised concerns about the possible emergence of drug-resistant schistosomes. …
Diversification of Ig superfamily genes in an invertebrate
The freshwater snail Biomphalaria glabrata possesses a diverse family of fibrinogen-related
proteins (FREPs), hemolymph polypeptides that consist of one or two amino-terminal …
proteins (FREPs), hemolymph polypeptides that consist of one or two amino-terminal …
A family of fibrinogen-related proteins that precipitates parasite-derived molecules is produced by an invertebrate after infection
After infection with the digenetic trematode Echinostoma paraensei, hemolymph of the snail
Biomphalaria glabrata contains lectins comprised of 65-kDa subunits that precipitate …
Biomphalaria glabrata contains lectins comprised of 65-kDa subunits that precipitate …
[HTML][HTML] Whole genome analysis of a schistosomiasis-transmitting freshwater snail
Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma
mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global …
mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global …
Review of 2022 WHO guidelines on the control and elimination of schistosomiasis
Schistosomiasis is a helminthiasis infecting approximately 250 million people worldwide. In
2001, the World Health Assembly (WHA) 54.19 resolution defined a new global strategy for …
2001, the World Health Assembly (WHA) 54.19 resolution defined a new global strategy for …
Evolutionary relationships and biogeography of Biomphalaria (Gastropoda: Planorbidae) with implications regarding its role as host of the human bloodfluke …
…, BV Hofkin, GM Mkoji, ES Loker - Molecular biology …, 2001 - academic.oup.com
The wide geographic distribution of Schistosoma mansoni, a digenetic trematode and parasite
of humans, is determined by the occurrence of its intermediate hosts, freshwater snails of …
of humans, is determined by the occurrence of its intermediate hosts, freshwater snails of …
Role for a somatically diversified lectin in resistance of an invertebrate to parasite infection
Invertebrates lack adaptive immune systems homologous to those of vertebrates, yet it is
becoming increasingly clear that they can produce diversified antigen recognition molecules. …
becoming increasingly clear that they can produce diversified antigen recognition molecules. …
A comparative study of the life-histories of mammalian schistosomes
ES Loker - Parasitology, 1983 - cambridge.org
Available data in the literature pertaining to the life-history characteristics of all known
species of mammalian schistosomes have been gathered, and correlations between such …
species of mammalian schistosomes have been gathered, and correlations between such …
Towards an understanding of the mechanism of action of praziquantel
…, SD Melman, T Goronga, T Webb, ES Loker… - Molecular and …, 2009 - Elsevier
Although praziquantel (PZQ) has been used to treat schistosomiasis for over 20 years its
mechanism of action remains unknown. We have developed an assay based on the …
mechanism of action remains unknown. We have developed an assay based on the …