Purpose.: To examine sex-and race-associated differences in macular thickness and foveal
pit morphology by using spectral-domain optical coherence tomography (SD-OCT). Methods.…

Peters anomaly is a form of anterior segment dysgenesis characterized by central ocular
opacity and corneo‐lenticular adhesions. Isolated and syndromic Peters anomaly can be …

Peters anomaly is a rare form of anterior segment ocular dysgenesis, which can also be
associated with additional systemic defects. At this time, the majority of cases of Peters anomaly …

Peters plus syndrome ( PPS ) is a rare autosomal‐recessive disorder characterized by
Peters anomaly of the eye, short stature, brachydactyly, dysmorphic facial features, …

Mutations in FOXC1 and PITX2 constitute the most common causes of ocular anterior segment
dysgenesis (ASD), and confer a high risk for secondary glaucoma. The genetic causes …

Photoreceptor death is the ultimate cause of vision loss in many retinal degenerative conditions.
Identifying novel therapeutic avenues for prolonging photoreceptor health and function …

Synthetic high-density lipoprotein (sHDL) and rapamycin (Rap) have both been shown to
be potential treatments for age-related macular degeneration (AMD). The low aqueous …

HK2 and PKM2 are two main regulators of aerobic glycolysis. Photoreceptors (PRs) use
aerobic glycolysis to produce the biomass necessary for the daily renewal of their outer …

Photoreceptor cell death is the ultimate cause of vision loss in many retinal disorders, and
there is an unmet need for neuroprotective modalities to improve photoreceptor survival. …

Treatment options are lacking to prevent photoreceptor death and subsequent vision loss.
Previously, we demonstrated that reprogramming metabolism via the pharmacologic …