Resveratrol-based MTDLs to stimulate defensive and regenerative pathways and block early events in neurodegenerative cascades
…, A Pérez-Castillo, E Sastre… - Journal of Medicinal …, 2022 - ACS Publications
… Eric del Sastre Eric del Sastre Instituto Teófilo Hernando de I+D del Medicamento,
Departamento de Farmacología y Terapéutica, Facultad de Medicina, Universidad Autónoma de …
Departamento de Farmacología y Terapéutica, Facultad de Medicina, Universidad Autónoma de …
Intracellular calcium and inflammatory markers, mediated by purinergic stimulation, are differentially regulated in monocytes of patients with major depressive disorder
…, YS Carro, MC Ovejero-Benito, E Del Sastre… - Neuroscience …, 2021 - Elsevier
The P2X7 receptor (P2X7R) is a ligand-gated ion channel that is being recognized as a major
player in neuropsychiatric disorders such as Major Depressive Disorder (MDD). P2X7R …
player in neuropsychiatric disorders such as Major Depressive Disorder (MDD). P2X7R …
[HTML][HTML] Nicotianamine Synthase 2 Is Required for Symbiotic Nitrogen Fixation in Medicago truncatula Nodules
V Escudero, I Abreu, E Del Sastre… - Frontiers in Plant …, 2020 - frontiersin.org
Symbiotic nitrogen fixation carried out by the interaction between legumes and diazotrophic
bacteria known as rhizobia requires relatively large levels of transition metals. These …
bacteria known as rhizobia requires relatively large levels of transition metals. These …
Brain Vasculature Accumulates Tau and Is Spatially Related to Tau Tangle Pathology in Alzheimer's Disease
Z Hoglund, N Ruiz-Uribe, E Del Sastre, B Woost… - bioRxiv, 2024 - biorxiv.org
Insoluble pathogenic proteins accumulate along blood vessels in conditions of cerebral
amyloid angiopathy (CAA), exerting a toxic effect on vascular cells and impacting cerebral …
amyloid angiopathy (CAA), exerting a toxic effect on vascular cells and impacting cerebral …
[HTML][HTML] Microglial hemoxygenase-1 deletion reduces inflammation in the retina of old mice with tauopathy
…, JA Matamoros, C Fernández-Mendívil, E Del Sastre… - Antioxidants, 2022 - mdpi.com
Tauopathies such as Alzheimer’s disease are characterized by the accumulation of
neurotoxic aggregates of tau protein. With aging and, especially, in Alzheimer’s patients, the …
neurotoxic aggregates of tau protein. With aging and, especially, in Alzheimer’s patients, the …
Non conventional targets for the treatment of Alzheimer's disease
…, P Trigo, C Fernández-Mendívil, F Franco, E Sastre… - 2019 - digital.csic.es
Alzheimer’s disease (AD) is becoming a devastating health, social, and economical problem.
Burden to society will increase as population ages. The search of diseasemodifying drugs …
Burden to society will increase as population ages. The search of diseasemodifying drugs …
Proposals for Improving Assessment Systems in Higher Education: An Approach from the Model" Working with People".
I de los Ríos-Carmenado, S Sastre-Merino… - Journal of Technology …, 2016 - ERIC
The European Higher Education Area (EHEA) represents a challenge to university teachers
to adapt their assessment systems, directing them towards continuous assessment. The …
to adapt their assessment systems, directing them towards continuous assessment. The …
Efficient parallelization of a regional ocean model for the western Mediterranean Sea
…, J Arnaiz, R Bermejo, PG Del Sastre - … journal of high …, 2014 - journals.sagepub.com
This paper focuses on the parallelization of an ocean model applying current multicore
processor-based cluster architectures to an irregular computational mesh. The aim is to maximize …
processor-based cluster architectures to an irregular computational mesh. The aim is to maximize …
Study for the computational resolution of different conduction heat transfer and fluid flow problems
E Sastre Rienitz - 2021 - upcommons.upc.edu
The main goal of the project is to develop a set of numerical tools using C++ that finally
permit to solve the Navier-Stokes equations in some specific cases. The fact of not using …
permit to solve the Navier-Stokes equations in some specific cases. The fact of not using …
ARIA‐EAACI statement on asthma and COVID‐19 (June 2, 2020)
To the Editor, A novel strain of human coronaviruses, the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), named by the International Committee on Taxonomy of …
coronavirus 2 (SARS-CoV-2), named by the International Committee on Taxonomy of …